重组人KAR蛋白(ab132771)
Key features and details
- Expression system: Wheat germ
- Suitable for: SDS-PAGE, ELISA, WB
描述
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产品名称
重组人KAR蛋白 -
表达系统
Wheat germ -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLG EWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEISNYT -
预测分子量
37 kDa including tags -
氨基酸
1 to 98
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技术指标
Our Abpromise guarantee covers the use of ab132771 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
ELISA
Western blot
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形式
Liquid -
补充说明
This product was previously labelled as HSD17B12.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- 12,3-ketoacyl-CoA reductase,short chain
- 17 beta HSD 12
- 17 beta hydroxysteroid dehydrogenase 12
see all -
功能
Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation. -
组织特异性
Expressed in most tissues tested. Highly expressed in the ovary and mammary. Expressed in platelets. -
通路
Steroid biosynthesis; estrogen biosynthesis.
Lipid metabolism; fatty acid biosynthesis. -
序列相似性
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. -
结构域
The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins. -
细胞定位
Endoplasmic reticulum membrane. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human KAR protein (ab132771)12.5% SDS-PAGE analysis of ab132771 stained with Coomassie Blue.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab132771 尚未被引用在任何文献中。
