重组人IPL-1/STK13/Aurora C蛋白(ab63177)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 80% Densitometry
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
描述
-
产品名称
重组人IPL-1/STK13/Aurora C蛋白
参阅全部 IPL-1/STK13/Aurora C 蛋白酶 -
生物活性
Specific activity 65nmol/min/mg
-
纯度
> 80 % Densitometry.
Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Human
-
相关产品
-
Related Products
-
Substrate reagent
技术指标
Our Abpromise guarantee covers the use of ab63177 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
Functional Studies
-
形式
Liquid -
补充说明
ab43614 (Human Myelin Basic Protein full length protein) can be utilized as a substrate for assessing Kinase activity
-
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
-
别名
- AURKC
- AIE 2
- Aie1
see all -
功能
May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. May also contribute to the regulation of chromosome segregation and cytokinesis. -
组织特异性
Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Expression is maximum at M phase. -
疾病相关
Defects in AURKC are the cause of male infertility with large-headed multiflagellar polyploid spermatozoa (MIMPS) [MIM:243060]; also known as infertility associated with multi-tailed spermatozoa and excessive DNA. -
序列相似性
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
Contains 1 protein kinase domain. -
细胞定位
Chromosome. Cytoplasm > cytoskeleton > spindle. Distributes in the condensed chromosomes during prophase to metaphase. After entering anaphase, there is a dissociation from separated chromosomes and a redistribution to midzone microtubules, and finally remaines in the midbody during cytokinesis. - Information by UniProt
图片
-
Functional Studies - Recombinant human IPL-1/STK13/Aurora C protein (ab63177)The specific activity of IPL-1/STK13/Aurora C (ab63177) was determined to be 65 nmol/min/mg as per activity assay protocol
-
SDS-PAGE - Recombinant human IPL-1/STK13/Aurora C protein (ab63177)SDS PAGE analysis of ab63177 -
SDS-PAGE - Recombinant human IPL-1/STK13/Aurora C protein (ab63177)SDS PAGE analysis of ab63177 -
Functional Studies - Recombinant human IPL-1/STK13/Aurora C protein (ab63177)Kinase activity plot -
SDS-PAGE - Recombinant human IPL-1/STK13/Aurora C protein (ab63177)ab63177 on SDS-PAGE, MW ~61 kDa
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab63177 尚未被引用在任何文献中。