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AB288525

重组人IL-34蛋白(Active)

Recombinant Human IL-34 protein (Active)

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Recombinant Human IL-34 protein (Active) is a Human Full Length protein, in the 21 to 242 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS, Mass Spec, HPLC, Cell Culture.

查看别名

C16orf77, IL34, Interleukin-34, IL-34

4 Images
Mass Spectrometry - Recombinant Human IL-34 protein (Active) (AB288525)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human IL-34 protein (Active) (AB288525)

ESI TOF analysis of ab288525.

Predicted MW is 25289.0 Da (+/- 10 Da by ESI TOF). Observed MW is25290.13

Functional Studies - Recombinant Human IL-34 protein (Active) (AB288525)
  • FuncS

Supplier Data

Functional Studies - Recombinant Human IL-34 protein (Active) (AB288525)

Fully biologically active determined by dose dependent proliferation of PBMCs cells. ED50 is ≤2.082 ng/ml, corresponding to a specific activity of 4.8 x 105 units/mg.

HPLC - Recombinant Human IL-34 protein (Active) (AB288525)
  • HPLC

Supplier Data

HPLC - Recombinant Human IL-34 protein (Active) (AB288525)

HPLC analysis of ab288525.

SDS-PAGE - Recombinant Human IL-34 protein (Active) (AB288525)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human IL-34 protein (Active) (AB288525)

SDS-PAGE analysis of ab288525.

关键信息

纯度

>95% SDS-PAGE

Purity by HPLC =95%

内毒素水平

<0.005 EU/µg

表达系统

HEK 293 cells

标签

Tag free

应用

FuncS, HPLC, Cell Culture, SDS-PAGE, Mass Spec

applications

生物活性

Yes

生物学活性

Fully biologically active determined by dose dependent proliferation of PBMCs cells. ED50 is ≤2.082 ng/ml, corresponding to a specific activity of 4.8 x 105 units/mg.

访问

Q6ZMJ4

不含动物源

Yes

不含载体蛋白

No

种属

Human

复溶

Reconstitute in PBS

存储溶液

pH: 7.4 Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic

storage-buffer

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搭配使用产品

Reagents, Controls & Accessories

AB313995

Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa) (AB313995)

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AB50036

Recombinant human TGF beta 1 protein (Active)

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AB259396

Recombinant human M-CSF protein (Active)

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Mass Spectrometry - Recombinant human M-CSF protein (Active) (AB259396)

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AB259376

Recombinant human GM-CSF protein (Active)

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Mass Spectrometry - Recombinant human GM-CSF protein (Active) (AB259376)

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Proteins & Peptides

AB290831

Recombinant Human TREM2 protein

SDS-PAGE - Recombinant Human TREM2 protein (AB290831)

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  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Cell Culture": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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序列信息

[{"linker":null,"sequence":"NEPLEMWPLTQNEECTVTGFLRDKLQYRSRLQYMKHYFPINYKISVPYEGVFRIANVTRLQRAQVSERELRYLWVLVSLSATESVQDVLLEGHPSWKYLQEVETLLLNVQQGLTDVEVSPKVESVLSLLNAPGPNLKLVRPKALLDNCFRVMELLYCSCCKQSSVLNWQDCEVPSPQSCSPEPSLQYAATQLYPPPPWSPSSPPHSTGSVRPVRAQGEGLLP","proteinLength":"Full Length","predictedMolecularWeight":"25.29 kDa","actualMolecularWeight":"25.9 kDa","aminoAcidEnd":242,"aminoAcidStart":21,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q6ZMJ4","tags":[]}]
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性能和储存信息

形式
Lyophilized
运输条件
Ambient - Can Ship with Ice
推荐的短期储存条件
Ambient
推荐的长期储存条件
Ambient
True
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常规信息

功能

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

序列相似性

Belongs to the IL-34 family.

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产品实验方案

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靶点信息

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
See full target information IL34
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Abcam Product Promise

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