重组人IL-2蛋白(ab119439)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: WB, ELISA, Functional Studies, SDS-PAGE, HPLC
描述
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产品名称
重组人IL-2蛋白
参阅全部 IL-2 蛋白酶 -
生物活性
1 x 107 units/mg
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纯度
> 98 % SDS-PAGE.
Purity >98% by SDS PAGE and HPLC sequence analysis. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
预测分子量
15 kDa -
氨基酸
21 to 153
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab119439 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
ELISA
Functional Studies
SDS-PAGE
HPLC
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形式
Lyophilized -
补充说明
Endotoxin Level: <0.1 ng/ug
Store at -20°C prior to reconstitution -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle. Reconstitute for long term storage.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶Reconstitute with 0.1ml 0.1M acetic acid. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
常规信息
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别名
- Aldesleukin
- IL 2
- IL-2
see all -
功能
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. -
疾病相关
Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. -
序列相似性
Belongs to the IL-2 family. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (2)
ab119439 被引用在 2 文献中.
- Grant NL et al. Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas. mBio 14:e0047723 (2023). PubMed: 37039646
- Xie L et al. P108 and T109 on E2 Glycoprotein Domain I Are Critical for the Adaptation of Classical Swine Fever Virus to Rabbits but Not for Virulence in Pigs. J Virol 94:N/A (2020). PubMed: 32581110