重组人IL-17 (IL-17A)蛋白(ab9567)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
描述
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产品名称
重组人IL-17 (IL-17A)蛋白
参阅全部 IL-17A 蛋白酶 -
生物活性
Assay #1: Measured by its ability to induce IL-6 production by NHDF cells, using a concentration range of 0.5-1.5 ng/ml.
Assay #2: Measured by its ability to induce GROα production by HT-29 cells, using a concentration range of 0.5-5.0 ng/ml. -
纯度
> 98 % SDS-PAGE.
Sterile filtered Greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg). -
内毒素水平
< 1.000 Eu/µg -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA -
预测分子量
17 kDa -
氨基酸
20 to 155
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描述
重组人IL-17A蛋白
相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab9567 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
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形式
Lyophilized -
补充说明
Measured by its ability to induce IL6 production by NHDF cells, using a concentration range of 0.5-1.5 ng/ml.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.
常规信息
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别名
- CTLA 8
- CTLA-8
- CTLA8
see all -
功能
Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. -
组织特异性
Restricted to activated memory T-cells. -
序列相似性
Belongs to the IL-17 family. -
翻译后修饰
Found both in glycosylated and nonglycosylated forms. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (4)
ab9567 被引用在 4 文献中.
- Morales-Soto W et al. Enteric glia promote visceral hypersensitivity during inflammation through intercellular signaling with gut nociceptors. Sci Signal 16:eadg1668 (2023). PubMed: 37988454
- Wang Z et al. Role of miR-106-mediated mitogen-activated protein kinase signaling pathway in oxidative stress injury and inflammatory infiltration in the liver of the mouse with gestational hypertension. J Cell Biochem N/A:N/A (2019). PubMed: 31773798
- Wang W et al. Astilbin reduces ROS accumulation and VEGF expression through Nrf2 in psoriasis-like skin disease. Biol Res 52:49 (2019). PubMed: 31492195
- Lv Q et al. Interleukin-17A and heparanase promote angiogenesis and cell proliferation and invasion in cervical cancer. Int J Oncol 53:1809-1817 (2018). PubMed: 30066843
