重组人IKZF3蛋白(ab132618)
Key features and details
- Expression system: Wheat germ
- Suitable for: ELISA, SDS-PAGE, WB
描述
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产品名称
重组人IKZF3蛋白 -
表达系统
Wheat germ -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPAN EDEDIGDDSMKVKDEYSERDENVLKSEPMGNAEEPEIPYSYSREYNEYEN IKLERHVVSFDSSRPTSGKMNCDVCGLSCISFNVLMVHKRSHTGERPFQC NQCGASFTQKGNLLRHIKLHTGEKPFKCHLCNYACQRRDALTGHLRTHSV EKPYKCEFCGRSYKQRSSLEEHKERCRTFLQSTDPGDTASAEARHIKAEM GSERALVLDRLASNVAKRKSSMPQKFIGEKRHCFDVNYNSSYMYEKESEL IQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTR AEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQN HIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEV MDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSH IARGEHRALLK -
预测分子量
82 kDa including tags -
氨基酸
1 to 509
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相关产品
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Matched antibody pairs
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab132618 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
ELISA
SDS-PAGE
Western blot
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- AIO
- Aiolos
- IKAROS family zinc finger 3
see all -
功能
Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. -
组织特异性
Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus. -
序列相似性
Belongs to the Ikaros C2H2-type zinc-finger protein family.
Contains 6 C2H2-type zinc fingers. -
翻译后修饰
Phosphorylation on tyrosine residues induced by IL2 is required for dissociation from HRAS and nuclear translocation of IKZF3 in T-cells. Phosphorylation on tyrosine residues induced by IL4 is required for dissociation from Bcl-X(L) in T-cells. -
细胞定位
Nucleus. Cytoplasm. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human IKZF3 protein (ab132618)12.5% SDS-PAGE analysis of ab132618 stained with Coomassie Blue.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab132618 尚未被引用在任何文献中。
