重组人IGFBP5蛋白(ab49835)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 0.100 Eu/µg
- Suitable for: WB, Inhibition Assay, Functional Studies, SDS-PAGE
描述
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产品名称
重组人IGFBP5蛋白 -
纯度
> 95 % SDS-PAGE.
Greater than 98% by SDS-PAGE gel and HPLC analyses. -
内毒素水平
< 0.100 Eu/µg -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
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技术指标
Our Abpromise guarantee covers the use of ab49835 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
Inhibition Assay
Functional Studies
SDS-PAGE
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituent: 0.294% Sodium citrate
Endotoxin level is less than 0.1 ng per µg (1EU/µg). -
复溶Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
常规信息
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别名
- IBP 5
- IBP-5
- IBP5
see all -
功能
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. -
组织特异性
Osteosarcoma, and at lower levels in liver, kidney and brain. -
序列相似性
Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain. -
细胞定位
Secreted. - Information by UniProt
图片
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Western blot - Recombinant Human IGFBP5 protein (ab49835)
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (2)
ab49835 被引用在 2 文献中.
- Slocum E et al. Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2. Breast Cancer Res 21:56 (2019). PubMed: 31046834
- Abrass CK & Hansen KM Insulin-like growth factor-binding protein-5-induced laminin gamma1 transcription requires filamin A. J Biol Chem 285:12925-34 (2010). PubMed: 20167606
