Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 0.100 Eu/µg
- Suitable for: WB, Inhibition Assay, Functional Studies, SDS-PAGE
纯度> 95 % SDS-PAGE.
Greater than 98% by SDS-PAGE gel and HPLC analyses.
内毒素水平< 0.100 Eu/µg
蛋白长度Full length protein
序列MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
Our Abpromise guarantee covers the use of ab49835 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituent: 0.294% Sodium citrate
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
复溶Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
- IBP 5
功能IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
组织特异性Osteosarcoma, and at lower levels in liver, kidney and brain.
序列相似性Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab49835 被引用在 2 文献中.
- Slocum E et al. Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2. Breast Cancer Res 21:56 (2019). PubMed: 31046834
- Abrass CK & Hansen KM Insulin-like growth factor-binding protein-5-induced laminin gamma1 transcription requires filamin A. J Biol Chem 285:12925-34 (2010). PubMed: 20167606