重组人Iba1蛋白(ab173043)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: = 1.000 Eu/µg
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE, HPLC
描述
-
产品名称
重组人Iba1蛋白
参阅全部 Iba1 蛋白酶 -
纯度
> 95 % SDS-PAGE.
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. -
内毒素水平
= 1.000 Eu/µg -
表达系统
Escherichia coli -
Accession
-
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
序列
SQTRDLQGGKAFGLLKAQQEERLDEINKQFLDDPKYSSDEDLPSKLEGFK EKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETF SYPDFLRMMLGKRSAILKMILMYEEKAREKEKPTGPPAKKAISELP -
预测分子量
18 kDa including tags -
氨基酸
2 to 147 -
标签
His tag C-Terminus
-
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab173043 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
HPLC
-
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS
Supplied as a 0.2 µm Ø filtered solution.
常规信息
-
别名
- AIF 1
- AIF-1
- Aif1
see all -
功能
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. -
组织特异性
Detected in T-lymphocytes and peripheral blood mononuclear cells. -
序列相似性
Contains 2 EF-hand domains. -
翻译后修饰
Phosphorylated on serine residues. -
细胞定位
Cytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (0)
ab173043 尚未被引用在任何文献中。
