重组人HRG beta 1蛋白(ab55742)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Suitable for: SDS-PAGE, Functional Studies
描述
-
产品名称
重组人HRG beta 1蛋白
参阅全部 HRG beta 1 蛋白酶 -
纯度
> 98 % SDS-PAGE.
purification checked by SDS Page and HPLC. -
表达系统
Escherichia coli -
蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
序列
SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQ NYVM ASFYKHLGIE FMEAE
-
技术指标
Our Abpromise guarantee covers the use of ab55742 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
Functional Studies
-
形式
Lyophilized -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
-
复溶Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
常规信息
-
别名
- Acetylcholine receptor inducing activity
- ARIA
- Breast cancer cell differentiation factor p45
see all -
相关性
HRG beta 1 is an isoform from the Neuregulin/Heregulin family of structurally related polypeptide growth factors which are derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentialtion of epithelial, neuronal, glial, and other types of cells. HRG1-ß1 contains an Ig domain and an EGF-like domain that is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. Although HRG1-ß1 biological effects are still unclear, it has been found to promote motility and invasiveness of breast cancer cells which may also involve up-regulation of expression and function of the autocrine motility promoting factor (AMF). -
细胞定位
Secreted
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (0)
ab55742 尚未被引用在任何文献中。
