重组人hnRNP A2B1蛋白(ab224866)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组人hnRNP A2B1蛋白
参阅全部 hnRNP A2B1 蛋白酶 -
纯度
> 90 % SDS-PAGE. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSR GFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVK KLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDD HDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEDLEVAILEVAPVMEEEE EDMVVEDLDMATRVGATEVVMTTMEEEIMEVEITMILEIITSNLLTTVQ -
预测分子量
55 kDa including tags -
氨基酸
1 to 249 -
标签
GST tag N-Terminus -
额外的序列信息
(BC000506).
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab224866 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: 50% Glycerol (glycerin, glycerine), Tris buffer
常规信息
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别名
- Heterogeneous nuclear ribonucleoprotein A2
- Heterogeneous nuclear ribonucleoprotein A2/B1
- Heterogeneous nuclear ribonucleoprotein B1
see all -
功能
Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleous. -
序列相似性
Contains 2 RRM (RNA recognition motif) domains. -
细胞定位
Nucleus > nucleoplasm. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Predominantly nucleoplasmic, however isoform A2 is also found in the cytoplasm of cells in some tissues. Not found in the nucleolus. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human hnRNP A2B1 protein (ab224866)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab224866 被引用在 3 文献中.
- Frederiksen SB et al. Identification of SRSF10 as a regulator of SMN2 ISS-N1. Hum Mutat 42:246-260 (2021). PubMed: 33300159
- Grønning AGB et al. DeepCLIP: predicting the effect of mutations on protein-RNA binding with deep learning. Nucleic Acids Res 48:7099-7118 (2020). PubMed: 32558887
- Bruun GH et al. Blocking of an intronic splicing silencer completely rescues IKBKAP exon 20 splicing in familial dysautonomia patient cells. Nucleic Acids Res 46:7938-7952 (2018). PubMed: 29762696