重组人HIP1R蛋白(ab131891)
Key features and details
- Expression system: Wheat germ
- Suitable for: WB, SDS-PAGE, ELISA
描述
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产品名称
重组人HIP1R蛋白 -
表达系统
Wheat germ -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MNSIKNVPARVLSRRPGHSLEAEREQFDKTQAISISKAINTQEAPVKEKH ARRIILGTHHEKGAFTFWSYAIGLPLPSSSILSWKFCHVLHKVLRDGHPN VLHDCQRYRSNIREIGDLWGHLHDRYGQLVNVYTKLLLTKISFHLKHPQF PAGLEVTDEVLEKAAGTDVNNIFQLTVEMFDYMDCELKLSESVFRQLNTA IAVSQMSSGQCRLAPLIQVIQDCSHLYHYTVKLLFKLHSCLPADTLQGHR DRFHEQFHSLRNFFRRASDMLYFKRLIQIPRLPEGPPNFLRASALAEHIK PVVVIPEEAPEDEEPENLIEISTGPPAGEPVVVADLFDQTFGPPNGSVKD DRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRK QKQKALVDNEQLRHELAQLRAAQLEGERSQGLREEAERKASATEARYNKL KEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVARVKEQLAFQVEQVK RESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQSKSELSSRLD TLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQG RLAERESQEQGLRQRLLDEQFAVLRGAAAEAAGILQDAVSKLDDPLHLRC TSSPDYLVSRAQEALDAVSTLEEGHAQYLTSLADASALVAALTRFSHLAA DTIINGGATSHLAPTDPADRLIDTCRECGARALELMGQLQDQQALRHMQA SLVRTPLQGILQLGQELKPKSLDVRQEELGAVVDKEMAATSAAIEDAVRR IEDMMNQARHASSGVKLEVNERILNSCTDLMKAIRLLVTTSTSLQKEIVE SGRGAATQQEFYAKNSRWTEGLISASKAVGWGATQLVEAADKVVLHTGKY EELIVCSHEIAASTAQLVAASKVKANKHSPHLSRLQECSRTVNERAANVV ASTKSGQEQIEDRDTMDFSGLSLIKLKKQEMETQVRVLELEKTLEAERMR LGELRKQHYVLAGASGSPGEEVAIRPSTAPRSVTTKKPPLAQKPSVAPRQ DHQLDKKDGIYPAQLVNY -
预测分子量
146 kDa including tags -
氨基酸
1 to 1068
-
技术指标
Our Abpromise guarantee covers the use of ab131891 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
SDS-PAGE
ELISA
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形式
Liquid -
补充说明
Protein concentration is above or equal to 0.05 ug/ul. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- FLJ14000
- FLJ27022
- HIP-12
see all -
功能
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. -
组织特异性
Brain, heart, kidney, pancreas, and liver, but not in lung or placenta. -
序列相似性
Belongs to the SLA2 family.
Contains 1 ENTH (epsin N-terminal homology) domain.
Contains 1 I/LWEQ domain. -
结构域
Binds F-actin via the talin-like I/LWEQ domain. -
细胞定位
Cytoplasm > perinuclear region. Endomembrane system. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human HIP1R protein (ab131891)12.5% SDS-PAGE stained with Coomassie Blue showing ab131891 at approximately 145.8 kDa.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab131891 尚未被引用在任何文献中。
