重组人HEC1/HEC蛋白(ab131907)
Key features and details
- Expression system: Wheat germ
- Suitable for: WB, SDS-PAGE, ELISA
描述
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产品名称
重组人HEC1/HEC蛋白 -
表达系统
Wheat germ -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MKRSSVSSGGAGRLSMQELRSQDVNKQGLYTPQTKEKPTFGKLSINKPTS ERKVSLFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLC EFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEE VPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKE SSPLFDDGQPWGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAEL QSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQEREKEPNRLESLRKLK ASLQGDVQKYQAYMSNLESHSAILDQKLNGLNEEIARVELECETIKQENT RLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQKLWNEELK YARGKEAIETQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCL VKYRAQVYVPLKELLNETEEEINKALNKKMGLEDTLEQLNAMITESKRSV RTLKEEVQKLDDLYQQKIKEAEEEDEKCASELESLEKHKHLLESTVNQGL SEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMVATHVGSVEKHL EEQIAKVDREYEECMSEDLSENIKEIRDKYEKKATLIKSSEE -
预测分子量
100 kDa including tags -
氨基酸
1 to 642
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab131907 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
SDS-PAGE
ELISA
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形式
Liquid -
补充说明
This product was previously labelled as HEC1.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- from Entrez Gene ;
- HEC
- Highly expressed in cancer
see all -
功能
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. -
序列相似性
Belongs to the NDC80/HEC1 family. -
发展阶段
Expression peaks in mitosis. -
翻译后修饰
Phosphorylation begins in S phase of the cell cycle and peaks in mitosis. Phosphorylated by NEK2. May also be phosphorylated by AURKA and AURKB. -
细胞定位
Nucleus. Chromosome > centromere > kinetochore. Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab131907 尚未被引用在任何文献中。