重组人 Grancalcin 蛋白 (His tag N-Terminus)
Recombinant Human Grancalcin protein (His tag N-Terminus)
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Recombinant Human Grancalcin protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 217 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
查看别名
GCL, GCA, Grancalcin
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human Grancalcin protein (His tag N-Terminus) (AB103054)
SDS-PAGE of ab103054 (3µg) under reducing condition and visualized by coomassie blue stain.
反应性数据
序列信息
性能和储存信息
运输条件
推荐的短期储存时间
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Grancalcin is involved in the regulation of cellular adhesion mechanisms. It does not form part of a larger protein complex but it plays a critical role in integrating calcium signals that facilitate cell function. Additionally grancalcin helps in the reorganization of the cytoskeleton impacting processes like chemotaxis and phagocytosis important for immune response.
Pathways
Grancalcin plays a role in the integrin signaling pathway. It interacts with key proteins in this pathway such as talin and vinculin to mediate cell adhesion and motility. Grancalcin's regulation of calcium signals also ties it to the MAPK signaling pathway which influences various cell functions including proliferation and differentiation.
特殊说明
形式
Liquid
附加说明
ab103054 was purified using conventional chromatography.
常规信息
功能
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
靶点信息
Abcam Product Promise
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