重组人GNAI2蛋白(ab132215)
Key features and details
- Expression system: Wheat germ
- Suitable for: WB, ELISA, SDS-PAGE
描述
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产品名称
重组人GNAI2蛋白
参阅全部 GNAI2 蛋白酶 -
表达系统
Wheat germ -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MEYAGHLPASSAQGTILACTSCTGAGESGKSTIVKQMKIIHEDGYSEEEC RQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEE QGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQS DYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCF EGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSII LFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKD TKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF -
预测分子量
63 kDa including tags -
氨基酸
1 to 339
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技术指标
Our Abpromise guarantee covers the use of ab132215 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
ELISA
SDS-PAGE
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形式
Liquid -
补充说明
This product was previously labelled as G protein alpha Inhibitor 2.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- Adenylate cyclase inhibiting G alpha protein
- Adenylate cyclase-inhibiting G alpha protein
- GIP
see all -
功能
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. -
序列相似性
Belongs to the G-alpha family. G(i/o/t/z) subfamily. -
细胞定位
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cell membrane. Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (1)
ab132215 被引用在 1 文献中.
- Chowdhury A et al. Role of PKCζ-NADPH oxidase signaling axis in PKCα-mediated Giα2 phosphorylation for inhibition of adenylate cyclase activity by angiotensin II in pulmonary artery smooth muscle cells. Cell Biol Int 44:1142-1155 (2020). PubMed: 31965656