重组人Glypican 3蛋白(Tagged) (ab271529)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 68% SDS-PAGE
- Tags: His tag C-Terminus, Avi tag C-Terminus
- Suitable for: WB, SDS-PAGE
描述
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产品名称
重组人Glypican 3蛋白(Tagged)
参阅全部 Glypican 3 蛋白酶 -
纯度
>= 68 % SDS-PAGE. -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
QPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCS RKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKN YTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSL FPVIYTQLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQ VTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPC GGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLF STIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVLK VAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLCWN GQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLR TMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLA ELAYDLDVDDAPGNSQQATPKDNEISTFHNLGNVH -
预测分子量
63 kDa -
氨基酸
25 to 559 -
标签
His tag C-Terminus , Avi tag C-Terminus -
额外的序列信息
Includes alpha and beta sunbunits.
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab271529 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 0.13% Sodium phosphate, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)
常规信息
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别名
- DGSX
- Glypican proteoglycan 3
- Glypican-3 [Precursor]
see all -
功能
Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. -
组织特异性
Highly expressed in lung, liver and kidney. -
疾病相关
Defects in GPC3 are the cause of Simpson-Golabi-Behmel syndrome type 1 (SGBS1) [MIM:312870]; also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies. -
序列相似性
Belongs to the glypican family. -
细胞定位
Cell membrane and Secreted > extracellular space. - Information by UniProt
图片
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Western blot - Recombinant Human Glypican 3 protein (Tagged) (ab271529)
Recombinant Human Glypican 3 protein (Tagged) (ab271529) used as positive control in WB.
Lane 1: Non-reducing conditions.
Lane 2: Reducing conditions.
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SDS-PAGE - Recombinant Human Glypican 3 protein (Tagged) (ab271529)SDS-PAGE analysis of 8 µg ab271529.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271529 尚未被引用在任何文献中。