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AB164034

重组人 GCC1 蛋白 (GST tag N-Terminus)

Recombinant Human GCC1 protein (GST tag N-Terminus)

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Recombinant Human GCC1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 775 aa range, expressed in Wheat germ, suitable for ELISA, WB.

查看别名

GRIP and coiled-coil domain-containing protein 1, Golgi coiled-coil protein 1, GCC1

1 Images
SDS-PAGE - Recombinant Human GCC1 protein (GST tag N-Terminus) (AB164034)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human GCC1 protein (GST tag N-Terminus) (AB164034)

ab164034 on a 12.5% SDS-PAGE stained with Coomassie Blue.

关键信息

表达系统

Wheat germ

标签

GST tag N-Terminus

应用

WB, ELISA

applications

生物活性

No

访问

Q96CN9

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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序列信息

[{"sequence":"MEKFGMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLSVSHEADVGLAGVQLPGLTFPDSVDDRCSTHSEDSTGTATSLDTAASLTSTKGEFGVEDDRPARGPPPPKSEEASWSESGVSSSSGDGPFAGGEVDKRLHQLKTQLATLTSSLATVTQEKSRMEASYLADKKKMKQDLEDASNKAEEERARLEGELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQEERTQRQDLELRLEETREALAGRAYAAEQMEGFELQTKQLTREVEELKSELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQISEVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGNLGKELEAAQEQLAELKEKYISLRLSCEELEHQHQQEADDWKQELARLQQLHRQELERCQLDFRDRTLKLEEELHKQRDRALAVLTEKDLELEQLRSVALASGLPGRRSPVGGGGPGDPADTSSSDSLTQALQLAAANEPTFFLYAEQLARKEVEITSLRKQKHRLEVEVHQLQDRLLEEGERHREEVAALQSHIEKNIRDQSREGANLEYLKNIIYRFLTLPDSLGRQQTLTAILTILHFSPEEKQVIMRLPTSASWWPSGKR","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":775,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q96CN9","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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性能和储存信息

运输条件
Dry Ice
推荐的短期储存条件
-80°C
推荐的长期储存条件
-80°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

GCC1 also known as Golgi coiled-coil protein 1 is a protein with a mass of approximately 82 kDa. It mainly localizes to the Golgi apparatus and plays a significant role in the Golgi structure and function. GCC1 engages with various proteins to support Golgi cisternal stacking and maintenance of Golgi morphology. It is expressed in multiple tissues with higher expression levels detected in organs with secretory functions.
Biological function summary

GCC1 interacts within protein complexes that govern the trafficking and sorting of proteins through the Golgi apparatus. It contributes to the regulation of retrograde transport moving proteins from the Golgi back to the endoplasmic reticulum. GCC1 partners with Rab GTPases which are vital for vesicle formation and cargo recognition therefore facilitating efficient intracellular transport and processing.

Pathways

GCC1 participates in critical cellular processes including the Golgi-to-ER retrograde transport and the broader protein secretion pathway. It works closely with proteins such as Rab6 which is necessary for the regulation of this pathway. Through these interactions GCC1 ensures optimal function and communication between cellular compartments involved in the secretory process.

GCC1 has associations with conditions such as neurodegenerative diseases and cancer. Aberrant expression or mutation of GCC1 may contribute to Golgi fragmentation which has been observed in various neurological disorders. Additionally GCC1 interactions with proteins like SNAREs may have implications in tumorigenesis as defects in vesicular transport can influence cancer progression.
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特殊说明

形式

Liquid

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常规信息

功能

Probably involved in maintaining Golgi structure.

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产品实验方案

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靶点信息

Probably involved in maintaining Golgi structure.
See full target information GCC1
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