重组人G蛋白-coupled receptor 20 variant

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

The GPR20 variant contributes to signal transduction processes that influence cellular responses. Researchers have not linked GPR20 to a specific ligand or described it as part of a receptor complex. It impacts cellular events through modulation of G protein activity affecting downstream signaling pathways. Although research on GPR20 is still expanding this receptor likely plays a role in normal physiological processes by influencing cellular communication.

Pathways

The signaling pathways influenced by GPR20 include the MAPK/ERK and GPCR signaling pathways. GPR20's activation can alter the signaling cascade of these pathways. Through MAPK/ERK GPR20 affects cell differentiation and proliferation while it helps mediate various cell responses in GPCR signaling. Proteins such as GRK (G protein-coupled receptor kinase) and arrestin interact with this receptor indirectly through these pathways acting as regulatory elements for signaling outcomes.