JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB78877

重组人 Ferritin Heavy Chain 蛋白 (Tag Free)

Recombinant Human Ferritin Heavy Chain protein (Tag Free)

Be the first to review this product! Submit a review

|

(2 Publications)

Recombinant Human Ferritin Heavy Chain protein (Tag Free) is a Human Full Length protein, in the 1 to 183 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, ELISA, WB.

查看别名

FTH, FTHL6, OK/SW-cl.84, PIG15, FTH1, Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein

2 Images
Western blot - Recombinant Human Ferritin Heavy Chain protein (Tag Free) (AB78877)
  • WB

Unknown

Western blot - Recombinant Human Ferritin Heavy Chain protein (Tag Free) (AB78877)

All lanes:

Western blot - Anti-Ferritin Heavy Chain antibody (<a href='/products/primary-antibodies/ferritin-heavy-chain-antibody-ab65080'>ab65080</a>) at 1 µg/mL

Lane 1:

Western blot - Recombinant Human Ferritin Heavy Chain protein (Tag Free) (ab78877) at 0.1 µg

Lane 2:

Western blot - Recombinant Human Ferritin Heavy Chain protein (Tag Free) (ab78877) at 0.01 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-preadsorbed-ab97080'>ab97080</a>) at 1/5000 dilution

Predicted band size: 21 kDa

true

Exposure time: 30s

SDS-PAGE - Recombinant Human Ferritin Heavy Chain protein (Tag Free) (AB78877)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human Ferritin Heavy Chain protein (Tag Free) (AB78877)

15% SDS-PAGE showing ab78877 at approximately 21kDa (3μg).

关键信息

纯度

>95% SDS-PAGE

表达系统

Escherichia coli

标签

Tag free

应用

ELISA, WB, SDS-PAGE

applications

生物活性

No

访问

P02794

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 7.5 Constituents: 10% Glycerol (glycerin, glycerine), 0.242% Tris, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

style
left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>ab78877 can be used as a WB positive control in conjunction with <a href='/products/primary-antibodies/ferritin-heavy-chain-antibody-ab65080'>ab65080</a>.</p>" } } }
style
left-column
style
left-column

序列信息

[{"sequence":"MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDNES","proteinLength":"Full Length","predictedMolecularWeight":"21 kDa","actualMolecularWeight":null,"aminoAcidEnd":183,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P02794","tags":[]}]
style
left-column

性能和储存信息

运输条件
Blue Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
style
left-column
style
left-column

特殊说明

形式

Liquid

附加说明

ab78877is purified using conventional chromatography techniques.

style
left-column

常规信息

功能

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed : 9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed : 9003196). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed : 24695223, PubMed : 26436293).

序列相似性

Belongs to the ferritin family.

亚细胞定位

Lysosome

style
left-column

产品实验方案

style
left-column

靶点信息

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed : 9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed : 9003196). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed : 24695223, PubMed : 26436293).
See full target information FTH1
style
left-column

文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Cell death discovery 8:426 PubMed36284090

2022

Ferrostatin-1 alleviates tissue and cell damage in diabetic retinopathy by improving the antioxidant capacity of the Xc-GPX4 system.

Applications

Unspecified application

Species

Unspecified reactive species

Jingzhi Shao,Zhouxian Bai,Lirong Zhang,Fengyan Zhang

Annals of the rheumatic diseases 71:943-7 PubMed22228484

2012

Association of ferritin autoantibodies with giant cell arteritis/polymyalgia rheumatica.

Applications

ELISA

Species

Unspecified reactive species

N T Baerlecken,A Linnemann,W L Gross,F Moosig,T R Vazquez-Rodriguez,M A Gonzalez-Gay,J Martin,I Kötter,J C Henes,I Melchers,P Vaith,R E Schmidt,T Witte
View all publications
style
left-column
style
left-column
style
right-column

搭配使用产品

Reagents, Controls & Accessories

AB313996

Prestained Protein Ladder - Extra broad molecular weight (3 - 260 kDa)

SDS-PAGE - Prestained Protein Ladder - Extra broad molecular weight (3 - 260 kDa) (AB313996)

  • 0
  • 0
Primary Antibodies

AB316005

Anti-TIP49A antibody [EPR28169-31] - BSA and Azide free

BOND RX™ Validated|Recombinant|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TIP49A antibody [EPR28169-31] - BSA and Azide free (AB316005)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB75973

Anti-Ferritin heavy chain antibody [EPR3004Y]

RabMAb|Recombinant|KO Validated

Western blot - Anti-Ferritin heavy chain antibody [EPR3004Y] (AB75973)

  • 4
  • 7
Proteins & Peptides

AB158473

Recombinant Human Ferritin Light Chain protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human Ferritin Light Chain protein (GST tag N-Terminus) (AB158473)

  • 0
  • 0

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com