重组人FAM38A/PIEZO1蛋白(ab132881)
Key features and details
- Expression system: Wheat germ
- Suitable for: WB, ELISA, SDS-PAGE
描述
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产品名称
重组人FAM38A/PIEZO1蛋白 -
表达系统
Wheat germ -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MKICPFSSKSSIVLALKFRSLIHFEKYPQPKGQKKKKIVKYGMGGLIILF LIAIIWFPLLFMSLVRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSI IPFTAQAYEELSRQFDPQPLAMQFISQYSPEDIVTAQIEGSSGALWRISP PSRAQMKRELYNGTADITLRFTWNFQRDLAKGGTVEYANEKHMLALAPNS TARRQLASLLEGTSDQSVVIPNLFPKYIRAPNGPEANPVKQLQPNEEADY LGVRIQLRREQGAGATGFLEWWVIELQECRTDCNLLPMVIFSDKHHGAVR VHRAGHRQVRARILQRDLALHYVRGAAVRGPHPQALPGHLPGAGDSGAGA GGGVVCQAHLPLPLTGDHDQVDS -
预测分子量
67 kDa including tags -
氨基酸
1 to 373
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技术指标
Our Abpromise guarantee covers the use of ab132881 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
ELISA
SDS-PAGE
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形式
Liquid -
补充说明
This product was previously labelled as FAM38A.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- DHS
- Fam38a
- Family with sequence similarity 38 member A
see all -
功能
Component of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling. -
组织特异性
Expressed in numerous tissues. In normal brain, expressed exclusively in neurons, not in astrocytes. In Alzheimer disease brains, expressed in about half of the activated astrocytes located around classical senile plaques. In Parkinson disease substantia nigra, not detected in melanin-containing neurons nor in activated astrocytes. -
序列相似性
Belongs to the PIEZO family. -
细胞定位
Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. Cell membrane. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab132881 尚未被引用在任何文献中。