重组人Ephrin B1蛋白(denatured) (ab111630)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组人Ephrin B1蛋白(denatured)
参阅全部 Ephrin B1 蛋白酶 -
纯度
> 90 % SDS-PAGE. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MGSSHHHHHHSSGLVPRGSHMLAKNLEPVSWSSLNPKFLSGKGLVIYPKI GDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQ EIRFTIKFQEFSPNYMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTR TMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAPGSRGSLGDSD GKHETVNQEEKSGPGASGGSSGDPDGFFNSK -
预测分子量
25 kDa including tags -
氨基酸
28 to 237 -
标签
His tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab111630 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00
Constituents: 2.4% Urea, 0.32% Tris HCl, 5% Glycerol (glycerin, glycerine)
常规信息
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别名
- CFND
- CFNS
- Craniofrontonasal syndrome (craniofrontonasal dysplasia)
see all -
功能
Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. -
组织特异性
Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas. -
疾病相关
Defects in EFNB1 are a cause of craniofrontonasal syndrome (CFNS) [MIM:304110]; also known as craniofrontonasal dysplasia (CFND). CFNS is an X-linked inherited syndrome characterized by hypertelorism, coronal synostosis with brachycephaly, downslanting palpebral fissures, clefting of the nasal tip, joint anomalies, longitudinally grooved fingernails and other digital anomalies. -
序列相似性
Belongs to the ephrin family. -
翻译后修饰
Inducible phosphorylation of tyrosine residues in the cytoplasmic domain. -
细胞定位
Membrane. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human Ephrin B1 protein (denatured) (ab111630)
15% SDS-PAGE showing ab111630 at approximately 25.3kDa (3µg).
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab111630 尚未被引用在任何文献中。