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AB162883

重组人 ELOVL2 蛋白 (GST tag N-Terminus)

Recombinant Human ELOVL2 protein (GST tag N-Terminus)

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Recombinant Human ELOVL2 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 296 aa range, expressed in Wheat germ, suitable for ELISA, WB.

查看别名

ELG3, SSC2, ELOVL2, Very long chain fatty acid elongase 2, 3-keto acyl-CoA synthase ELOVL2, ELOVL fatty acid elongase 2, Elongation of very long chain fatty acids protein 2, Very long chain 3-ketoacyl-CoA synthase 2, Very long chain 3-oxoacyl-CoA synthase 2, ELOVL FA elongase 2

1 Images
SDS-PAGE - Recombinant Human ELOVL2 protein (GST tag N-Terminus) (AB162883)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human ELOVL2 protein (GST tag N-Terminus) (AB162883)

ab162883 on a 12.5% SDS-PAGE stained with Coomassie Blue.

关键信息

表达系统

Wheat germ

标签

GST tag N-Terminus

应用

WB, ELISA

applications

生物活性

No

访问

Q9NXB9

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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搭配使用产品

Reagents, Controls & Accessories

AB313996

Prestained Protein Ladder - Extra broad molecular weight (3 - 260 kDa)

SDS-PAGE - Prestained Protein Ladder - Extra broad molecular weight (3 - 260 kDa) (AB313996)

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  • 0
Proteins & Peptides

AB316604

Recombinant Mouse Calprotectin Protein Standard (His tag)

Sandwich ELISA - Recombinant Mouse Calprotectin Protein Standard (His tag) (AB316604)

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  • 0
Primary Antibodies

AB45690

Anti-CCL4/MIP-1 beta antibody [EP521Y]

20ul selling size|RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-CCL4/MIP-1 beta antibody [EP521Y] (AB45690)

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  • 1
Primary Antibodies

AB59140

Anti-C8 antibody [056B-373]

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Proteins & Peptides

AB285976

Recombinant EN-TEV Protease protein

Bioactive

Functional Studies - Recombinant EN-TEV Protease protein (AB285976)

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  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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序列信息

[{"linker":null,"sequence":"MEHLKAFDDEINAFLDNMFGPRDSRVRGWFMLDSYLPTFFLTVMYLLSIWLGNKYMKNRPALSLRGILTLYNLGITLLSAYMLAELILSTWEGGYNLQCQDLTSAGEADIRVAKVLWWYYFSKSVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFVLAITHTMSAVVKPCGFPFGCLIFQSSYMLTLVILFLNFYVQTYRKKPMKKDMQEPPAGKEVKNGFSKAYFTAANGVMNKKAQ","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":296,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9NXB9","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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性能和储存信息

形式
Liquid
纯化工艺
Proprietary technique
运输条件
Dry Ice
推荐的短期储存条件
-80°C
推荐的长期储存条件
-80°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

The protein ELOVL2 also known as Elongation of very long chain fatty acids protein 2 plays an important role in the elongation of long-chain polyunsaturated fatty acids. Its molecular mass is approximately 33 kDa. ELOVL2 is expressed highly in the liver retina and testes indicating its importance in these tissues where long-chain fatty acids are critical.
Biological function summary

ELOVL2 functions in the biosynthesis of polyunsaturated fatty acids which are essential components of phospholipids and are involved in various cellular processes. Although ELOVL2 does not form part of a larger protein complex its enzymatic activity significantly impacts membrane fluidity and function. This fatty acid elongation process supports cellular homeostasis and influences signaling pathways.

Pathways

ELOVL2 serves a critical role in the fatty acid elongation pathway. Its activity is closely linked with enzymes like fatty acid desaturases which together maintain lipid composition within membranes. The function of ELOVL2 contributes importantly to the metabolism of fatty acids enabling the synthesis of eicosanoids and docosanoids which are vital signaling molecules.

ELOVL2 has been associated with age-related decline in physiological functions such as vision and metabolic syndromes like diabetes. Research suggests a connection between alterations in its activity with proteins such as FADS2 which participate in fatty acid metabolism can influence these conditions. Understanding the role of ELOVL2 in these diseases may offer potential therapeutic targets to mitigate their progression.
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常规信息

功能

Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20 : 4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

序列相似性

Belongs to the ELO family. ELOVL2 subfamily.

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产品实验方案

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靶点信息

Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20 : 4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
See full target information ELOVL2
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