重组人ELMO1蛋白(ab131839)
Key features and details
- Expression system: Wheat germ
- Suitable for: SDS-PAGE, ELISA, WB
描述
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产品名称
重组人ELMO1蛋白 -
表达系统
Wheat germ -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFA LQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAK LEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPC FGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQR SLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQTYTIAVINAL FLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKS MYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVL ENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDR SFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLD QFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQ QRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVP HDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNC QLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLD LENIQIPDAPPPIPKEPSNYDFVYDCN -
预测分子量
110 kDa including tags -
氨基酸
1 to 727
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab131839 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
ELISA
Western blot
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- CED 12
- Ced 12 homolog
- Ced 12 homolog 1
see all -
功能
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. -
组织特异性
Widely expressed, with a higher expression in the spleen and placenta. -
序列相似性
Contains 1 ELMO domain.
Contains 1 PH domain. -
翻译后修饰
Phosphorylated by HCK. -
细胞定位
Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab131839 尚未被引用在任何文献中。