重组人 ECH1 蛋白 (His tag N-Terminus)
Recombinant Human ECH1 protein (His tag N-Terminus)
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Recombinant Human ECH1 protein (His tag N-Terminus) is a Human Full Length protein, in the 34 to 328 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
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ECH1
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human ECH1 protein (His tag N-Terminus) (AB101154)
15% SDS-PAGE analysis of ab101154 (3μg)
反应性数据
序列信息
性能和储存信息
形式
运输条件
推荐的短期储存时间
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The ECH1 protein facilitates the breakdown and utilization of unsaturated fatty acids thereby providing energy for cellular processes. It acts independently and is not a part of a large protein complex. Mitochondria rely on ECH1 to handle specific intermediates in fatty acid metabolism which impacts how cells manage their energy resources. This makes ECH1 essential for maintaining energy homeostasis particularly during periods of increased metabolic demand.
Pathways
ECH1 is integral to the mitochondrial fatty acid beta-oxidation pathway. This pathway is important for converting fatty acids into acetyl-CoA units which then enter the Krebs cycle for further energy production. ECH1 interacts with other proteins like ACAA2 which contributes to the final step of fatty acid degradation. Alongside this it aligns with the peroxisomal biogenesis pathway influencing the balance between metabolic processes within mitochondria and peroxisomes.
常规信息
功能
Isomerization of 3-trans,5-cis-dienoyl-CoA (3E,5Z-dienoyl-CoA) to 2-trans,4-trans-dienoyl-CoA (2E,4E-dienoyl-CoA), a crucial step in the beta-oxidation of unsaturated fatty acids with double bonds at odd position.
序列相似性
Belongs to the enoyl-CoA hydratase/isomerase family.
亚细胞定位
Mitochondrion
靶点信息
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