重组人Dnmt3L蛋白- BSA and Azide free (ab180335)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, MS
描述
-
产品名称
重组人Dnmt3L蛋白- BSA and Azide free
参阅全部 Dnmt3L 蛋白酶 -
纯度
> 90 % SDS-PAGE.
ab180335 was purified using conventional chromatography. -
表达系统
Escherichia coli -
Accession
-
蛋白长度
Full length protein -
无动物成分
No -
无载体
是 -
性质
Recombinant -
-
种属
Human -
序列
MGSSHHHHHH SSGLVPRGSH MGSEFMAAIP ALDPEAEPSM DVILVGSSEL SSSVSPGTGR DLIAYEVKAN QRNIEDICIC CGSLQVHTQH PLFEGGICAP CKDKFLDALF LYDDDGYQSY CSICCSGETL LICGNPDCTR CYCFECVDSL VGPGTSGKVH AMSNWVCYLC LPSSRSGLLQ RRRKWRSQLK AFYDRESENP LEMFETVPVW RRQPVRVLSL FEDIKKELTS LGFLESGSDP GQLKHVVDVT DTVRKDVEEW GPFDLVYGAT PPLGHTCDRP PSWYLFQFHR LLQYARPKPG SPRPFFWMFV DNLVLNKEDL DVASRFLEME PVTIPDVHGG SLQNAVRVWS NIPAIRSRHW ALVSEEELSL LAQNKQSSKL AAKWPTKLVK NCFLPLREYF KYFSTELTSS L -
预测分子量
46 kDa including tags -
氨基酸
1 to 386 -
标签
His tag N-Terminus -
额外的序列信息
NP_787063
-
-
描述
重组人Dnmt3L蛋白(BSA and azide free)
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab180335 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
Mass Spectrometry
-
质谱法
MALDI-TOF -
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.32% Tris HCl, 0.88% Sodium chloride, 10% Glycerol (glycerin, glycerine), 0.02% DTT
常规信息
-
别名
- Cytosine 5 methyltransferase 3 like protein
- DNA (cytosine 5 ) methyltransferase 3 like
- DNA (cytosine-5)-methyltransferase 3-like
see all -
功能
Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3. -
组织特异性
Expressed at low levels in several tissues including testis, ovary, and thymus. -
序列相似性
Belongs to the C5-methyltransferase family.
Contains 1 ADD-type zinc finger. -
细胞定位
Nucleus. - Information by UniProt
图片
-
SDS-PAGE - Recombinant Human Dnmt3L protein - BSA and Azide free (ab180335)
15% SDS-PAGE analysis of ab180335 (3μg).
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab180335 尚未被引用在任何文献中。