重组人 Cytokeratin 5 蛋白 (GST tag N-Terminus)
Recombinant Human Cytokeratin 5 protein (GST tag N-Terminus)
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human Cytokeratin 5 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 590 aa range, expressed in Wheat germ, with >80%, suitable for SDS-PAGE, ELISA, WB.
查看别名
58 kDa cytokeratin, Cytokeratin-5, Keratin-5, Type-II keratin Kb5, CK-5, K5, KRT5, CK5
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human Cytokeratin 5 protein (GST tag N-Terminus) (AB132931)
12.5% SDS-PAGE analysis of ab132931 stained with Coomassie Blue
反应性数据
序列信息
性能和储存信息
运输条件
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
特殊说明
形式
Liquid
附加说明
Glutathione Sepharose
常规信息
功能
Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity).
序列相似性
Belongs to the intermediate filament family.
翻译后修饰
Phosphorylated by CDK1, AURKB and Rho-kinase, phosphorylation is regulated by the cell cycle (By similarity). Thr-24 phosphorylation, mediated by CDK1, peaks during prometaphase or metaphase cells with phosphorylated filamentous structures evident throughout the cytoplasm during early mitosis (By similarity). CDK1 phosphorylates Thr-24 in mitotic cells at the site of injury (By similarity).. O-glycosylated.
靶点信息
Abcam Product Promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com