重组人Cyclin A2蛋白
Recombinant Human Cyclin A2 protein
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Recombinant Human Cyclin A2 protein is a Human Full Length protein, in the 1 to 432 aa range, expressed in Baculovirus infected Sf9 cells, with >75%, suitable for SDS-PAGE.
查看别名
CCN1, CCNA, CCNA2, Cyclin-A2, Cyclin-A, Cyclin A
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human Cyclin A2 protein (AB125570)
SDS-PAGE analysis of ab125570.
反应性数据
序列信息
性能和储存信息
运输条件
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
特殊说明
形式
Liquid
附加说明
Purity was determined to be >75% by densitometry.
常规信息
功能
Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
序列相似性
Belongs to the cyclin family. Cyclin AB subfamily.
翻译后修饰
Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.
亚细胞定位
Nucleus
靶点信息
Abcam Product Promise
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