重组人CRMP4蛋白(ab132289)
Key features and details
- Expression system: Wheat germ
- Suitable for: SDS-PAGE, ELISA, WB
描述
-
产品名称
重组人CRMP4蛋白 -
表达系统
Wheat germ -
Accession
-
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
序列
MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLI VPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGG TTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQ EVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAE NGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPL YVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAA FVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTA IPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGR ISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQG KIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYD GPVFDLTTTPKGGTPAGSARGSPTRPNPPVRNLHQSGFSLSGTQVDEGVR SASKRIVAPPGGRSNITSLS -
预测分子量
88 kDa including tags -
氨基酸
1 to 570
-
技术指标
Our Abpromise guarantee covers the use of ab132289 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
ELISA
Western blot
-
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
-
别名
- Collapsin response mediator protein 4
- Collapsin response mediator protein 4 long
- CRMP 4
see all -
功能
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. -
组织特异性
Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. -
序列相似性
Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. -
翻译后修饰
Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3. -
细胞定位
Cytoplasm. Cell projection > growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. - Information by UniProt
图片
-
SDS-PAGE - Recombinant Human CRMP4 protein (ab132289)12.5% SDS-PAGE stained with Coomassie Blue showing ab132289.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (0)
ab132289 尚未被引用在任何文献中。
