AB183176

重组人 COMMD6 蛋白 (His tag N-Terminus)

Name: 重组人COMMD6蛋白 (ab183176)| Abcam中文官网
Brand: Abcam Limited
SKU: AB183176
Price: 5123 CNY
Availability: InStock

Recombinant Human COMMD6 protein (His tag N-Terminus)

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Recombinant Human COMMD6 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 85 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

查看别名

MSTP076, COMMD6, COMM domain-containing protein 6

关键信息

纯度

>90% SDS-PAGE

表达系统

Escherichia coli

应用

Mass Spec, SDS-PAGE

applications

生物活性

访问

Q7Z4G1

不含动物源

不含载体蛋白

种属

Human

存储溶液

pH: 7 Constituents: 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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序列信息

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQNFYRQFKEIAAVIETV","proteinLength":"Full Length","predictedMolecularWeight":"12.08 kDa","actualMolecularWeight":null,"aminoAcidEnd":85,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q7Z4G1","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

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性能和储存信息

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

False

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特殊说明

形式

Liquid

附加说明

ab183176 is purified using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20 mM Tris pH 7.5, 2 mM EDTA.

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常规信息

功能

Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (PubMed : 37172566, PubMed : 38459129). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed : 21778237). Down-regulates activation of NF-kappa-B (PubMed : 15799966, PubMed : 16573520). Inhibits TNF-induced NFKB1 activation (PubMed : 15799966, PubMed : 16573520).

序列相似性

Belongs to the COMM domain-containing protein 6 family.

亚细胞定位

Nucleus

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产品实验方案

Visit the General protocols
Visit the Troubleshooting

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靶点信息

See full target information COMMD6

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重组人 COMMD6 蛋白 (His tag N-Terminus)

Recombinant Human COMMD6 protein (His tag N-Terminus)

关键信息

纯度

表达系统

标签

应用

生物活性

访问

不含动物源

不含载体蛋白

种属

存储溶液