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AB106875

重组人 CLIC2 蛋白 (His tag N-Terminus)

Recombinant Human CLIC2 protein (His tag N-Terminus)

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(1 Publication)

Recombinant Human CLIC2 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 247 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

查看别名

Chloride intracellular channel protein 2, Glutaredoxin-like oxidoreductase CLIC2, Glutaredoxin-like peroxidase CLIC2, XAP121, CLIC2

2 Images
SDS-PAGE - Recombinant Human CLIC2 protein (His tag N-Terminus) (AB106875)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human CLIC2 protein (His tag N-Terminus) (AB106875)

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

SDS-PAGE - Recombinant Human CLIC2 protein (His tag N-Terminus) (AB106875)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human CLIC2 protein (His tag N-Terminus) (AB106875)

15% SDS-PAGE analysis of 3 μg ab106875.

关键信息

纯度

>95% SDS-PAGE

ab106875 was purified using conventional chromatography.

表达系统

Escherichia coli

标签

His tag N-Terminus

应用

Mass Spec, SDS-PAGE

applications

生物活性

No

访问

O15247

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.316% Tris HCl, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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搭配使用产品

Primary Antibodies

AB179461

Anti-JNK1 + JNK2 + JNK3 antibody [EPR16797-211]

20ul selling size|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-JNK1 + JNK2 + JNK3 antibody [EPR16797-211] (AB179461)

  • 4
  • 8
Primary Antibodies

AB175230

Anti-CLIC2 antibody [EPR6494]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLIC2 antibody [EPR6494] (AB175230)

  • 0
  • 0
Primary Antibodies

AB28849

Anti-NFkB p105 / p50 (phospho S337) antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NFkB p105 / p50 (phospho S337) antibody (AB28849)

  • 0
  • 0
Primary Antibodies

AB238137

Anti-IRF7 antibody [EPR23509-21]

20ul selling size|RabMAb|Recombinant

Immunoprecipitation - Anti-IRF7 antibody [EPR23509-21] (AB238137)

  • 0
  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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序列信息

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAKQKS","proteinLength":"Full Length","predictedMolecularWeight":"30.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":247,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"O15247","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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性能和储存信息

形式
Liquid
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
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常规信息

功能

In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Displays weak glutathione peroxidase activity (Probable) (PubMed : 25581026). Can insert into membranes and form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.

序列相似性

Belongs to the chloride channel CLIC family.

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产品实验方案

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靶点信息

In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Displays weak glutathione peroxidase activity (Probable) (PubMed : 25581026). Can insert into membranes and form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
See full target information CLIC2
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

CytoJournal 22:20 PubMed40134565

2025

Chloride intracellular channel 6 inhibits hepatocellular carcinoma progression by modulating immune cell balance and promoting tumor cell apoptosis.

Applications

Unspecified application

Species

Unspecified reactive species

He Zhou,Yue Xi,Xueyang Chen
View all publications
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