重组人CD97蛋白(ab131865)
Key features and details
- Expression system: Wheat germ
- Suitable for: ELISA, WB, SDS-PAGE
描述
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产品名称
重组人CD97蛋白 -
表达系统
Wheat germ -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSS FSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPV SGAKTFKNESENTCQDVDECSSGRHQCDSSTVCFNTVGSYSCRCRPGWKP RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSS AEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAK SLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAED PGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLS AVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQEL LCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE DWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVG STIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVR VFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAI AQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKV REEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI -
预测分子量
107 kDa including tags -
氨基酸
1 to 742
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技术指标
Our Abpromise guarantee covers the use of ab131865 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
ELISA
Western blot
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
常规信息
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别名
- ADGRE5
- Adhesion G protein-coupled receptor E5
- CD 97
see all -
功能
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. -
组织特异性
Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompagnied by detectable levels of soluble CD97 in the synovial fluid. -
序列相似性
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 5 EGF-like domains.
Contains 1 GPS domain. -
结构域
The first two EGF domains mediate the interaction with DAF. A third tandemly arranged EGF domain is necessary for the structural integrity of the binding region.
Binding to chondroitin sulfate is mediated by the fourth EGF domain. -
翻译后修饰
Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. -
细胞定位
Cell membrane and Secreted > extracellular space. - Information by UniProt
图片
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SDS-PAGE - Recombinant Human CD97 protein (ab131865)12.5% SDS-PAGE analysis of ab131865 stained with Coomassie Blue.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab131865 尚未被引用在任何文献中。
