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重组人CD8 alpha蛋白(ab114161)

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SDS-PAGE - Recombinant Human CD8 alpha protein (ab114161)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: WB, ELISA, SDS-PAGE

    描述

    • 产品名称

      重组人CD8 alpha蛋白
      参阅全部 CD8 alpha 蛋白酶

    • 表达系统

      Wheat germ

    • Accession

      P01732

    • 蛋白长度

      Protein fragment

    • 无动物成分

      No

    • 性质

      Recombinant

      • 种属

        Human

      • 序列

        SQFRVSPLDRTWNLGETVELKCQVLLSNPTSGCSWLFQPRGAAASPTFLL YLSQNKPKAAEGLDTQRFSGKRLGDTFVLTLSDFRRENEGYYFCSALSNS IMYFSHFVPV

      • 预测分子量

        38 kDa including tags

      • 氨基酸

        22 to 131

      • 标签

        GST tag N-Terminus

    相关产品

    技术指标

    Our Abpromise guarantee covers the use of ab114161 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      Western blot

      ELISA

      SDS-PAGE

    • 形式

      Liquid
    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.3% Glutathione, 0.79% Tris HCl

    常规信息

    • 别名

      • alpha polypeptide (p32)
      • CD_antigen=CD8a
      • CD8
      • CD8 antigen alpha polypeptide
      • CD8 antigen alpha polypeptide (p32)
      • CD8 antigen, alpha polypeptide (p32)
      • CD8a
      • CD8A antigen
      • CD8A molecule
      • CD8A_HUMAN
      • Leu2
      • Leu2 T lymphocyte antigen
      • Ly 2
      • Ly 35
      • Ly B
      • Ly2
      • Ly3
      • Ly35
      • LyB
      • Lyt 2.1 lymphocyte differentiation antigen (AA at 100)
      • LYT3
      • MAL
      • OKT8 T cell antigen
      • OTTHUMP00000160760
      • OTTHUMP00000160764
      • OTTHUMP00000203528
      • OTTHUMP00000203721
      • p32
      • T cell antigen Leu2
      • T cell co receptor
      • T lymphocyte differentiation antigen T8/Leu 2
      • T-cell surface glycoprotein CD8 alpha chain
      • T-cell surface glycoprotein Lyt 2
      • T-lymphocyte differentiation antigen T8/Leu-2
      • T8 T cell antigen
      • T8/Leu-2 T-lymphocyte differentiation antigen
      see all

    • 功能

      Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.

    • 疾病相关

      Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957]. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.

    • 序列相似性

      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • 翻译后修饰

      All of the five most carboxyl-terminal cysteines form inter-chain disulfide bonds in dimers and higher multimers, while the four N-terminal cysteines do not.

    • 细胞定位

      Secreted and Cell membrane.
    • Information by UniProt

    图片

    • SDS-PAGE - Recombinant Human CD8 alpha protein (ab114161)
      SDS-PAGE - Recombinant Human CD8 alpha protein (ab114161)
      12.5% SDS-PAGE analysis of ab114161, stained with Coomassie Blue.

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (0)

    发表研究结果有使用 ab114161？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab114161 尚未被引用在任何文献中。

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