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重组人CD74蛋白(His tag) (ab174039)

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SDS-PAGE - Recombinant Human CD74 protein (His tag) (ab174039)

    Key features and details

    • Expression system: HEK 293 cells
    • Purity: > 95% SDS-PAGE
    • Endotoxin level: < 1.000 Eu/µg
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE

    描述

    • 产品名称

      重组人CD74蛋白(His tag)
      参阅全部 CD74 蛋白酶

    • 纯度

      > 95 % SDS-PAGE.

    • 内毒素水平

      < 1.000 Eu/µg

    • 表达系统

      HEK 293 cells

    • Accession

      P04233-2

    • 蛋白长度

      Protein fragment

    • 无动物成分

      No

    • 性质

      Recombinant

      • 种属

        Human

      • 序列

        QQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPMGA LPQGPMQNATKYGNMTEDHVMHLLQNADPLKVYPPLKGSFPENLRHLKNT METIDWKVFESWMHHWLLFEMSRHSLEQKPTDAPPKESLELEDPSSGLGV TKQDLGPVPM

      • 预测分子量

        19 kDa including tags

      • 氨基酸

        73 to 232

      • 标签

        His tag N-Terminus

      • 额外的序列信息

        Human CD74, His Tag (CD4-H524c) is expressed from human 293 cells (HEK293). It contains AA Gln 73 - Met 232 (Accession # NP_004346.1).

    技术指标

    Our Abpromise guarantee covers the use of ab174039 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      SDS-PAGE

    • 形式

      Lyophilized

    • 补充说明

      Lyophilized from 0.22 μm filtered solution.

    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 95% PBS, 5% Trehalose

    • 复溶
      Reconstitute with sterile deionized water to a concentration of 400 µg/ml.

    常规信息

    • 别名

      • CD 74
      • CD74
      • CD74 antigen
      • CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
      • CD74 molecule
      • CD74 molecule, major histocompatibility complex, class II invariant chain
      • CLIP
      • DHLAG
      • Gamma chain of class II antigens
      • HG2A_HUMAN
      • HLA class II histocompatibility antigen gamma chain
      • HLA DR antigens associated invariant chain
      • HLA DR gamma
      • HLA-DR antigens-associated invariant chain
      • HLA-DR-gamma
      • HLADG
      • HLADR antigens associated invariant chain
      • Ia antigen associated invariant chain
      • Ia antigen-associated invariant chain
      • Ia associated invariant chain
      • Ia gamma
      • Ii
      • Invariant polypeptide of major histocompatibility complex class II antigen associated
      • la-gamma
      • Major histocompatibility complex class II invariant chain
      • MHC HLA DR gamma chain
      • MHC HLA-DR gamma chain
      • p33
      • p35
      • Protein 41
      see all

    • 功能

      Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

    • 序列相似性

      Contains 1 thyroglobulin type-1 domain.

    • 细胞定位

      Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus > trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.
    • Information by UniProt

    图片

    • SDS-PAGE - Recombinant Human CD74 protein (His tag) (ab174039)
      SDS-PAGE - Recombinant Human CD74 protein (His tag) (ab174039)
      SDS-PAGE analysis of ab174039 under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (0)

    发表研究结果有使用 ab174039？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab174039 尚未被引用在任何文献中。

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