重组人CD40蛋白(Active) (Biotin) (ab271432)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 90% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Tags: Avi tag C-Terminus, Fc tag C-Terminus
- Suitable for: Functional Studies, SDS-PAGE
描述
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产品名称
重组人CD40蛋白(Active) (Biotin)
参阅全部 CD40 蛋白酶 -
生物活性
Active in a CD40:CD40L binding assay.
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纯度
>= 90 % SDS-PAGE.
Aggregation state <10%. -
内毒素水平
< 1.000 Eu/µg -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
EPPTACREKQ YLINSQCCSL CQPGQKLVSD CTEFTETECL PCGESEFLDT WNRETHCHQH KYCDPNLGLR VQQKGTSETD TICTCEEGWH CTSEACESCV LHRSCSPGFG VKQIATGVSD TICEPCPVGF FSNVSSAFEK CHPWTSCETK DLVVQQAGTN KTDVVCGPQD RLR -
预测分子量
48 kDa -
氨基酸
21 to 193 -
标签
Avi tag C-Terminus , Fc tag C-Terminus -
额外的序列信息
Fc portion of Human IgG1. Genbank: NM_001250
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偶联物
Biotin
技术指标
Our Abpromise guarantee covers the use of ab271432 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
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形式
Liquid -
补充说明
Enzymatically biotin-labeled using Avi-tag™ technology
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle. Store In the Dark.
pH: 7.40
Constituents: 0.13% Sodium phosphate, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)This product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- AI326936
- B cell associated molecule CD40
- B cell surface antigen CD40
see all -
功能
Receptor for TNFSF5/CD40LG. -
组织特异性
B-cells and in primary carcinomas. -
疾病相关
Defects in CD40 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3) [MIM:606843]; also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation. -
序列相似性
Contains 4 TNFR-Cys repeats. -
细胞定位
Secreted and Cell membrane. - Information by UniProt
图片
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Functional Studies - Recombinant human CD40 protein (Active) (Biotin) (ab271432)
Functional analyss of ab271432 in a CD40:CD40L binding assay.
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SDS-PAGE - Recombinant Human CD40 protein (Tagged) (Biotin) (ab271432)SDS-PAGE analysis of ab271432.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271432 尚未被引用在任何文献中。