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AB105131

重组人 calcyphosine 蛋白 (His tag N-Terminus)

Recombinant Human calcyphosine protein (His tag N-Terminus)

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(1 Publication)

Recombinant Human calcyphosine protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 189 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

查看别名

Calcyphosin, Calcyphosine, CAPS

1 Images
SDS-PAGE - Recombinant Human calcyphosine protein (His tag N-Terminus) (AB105131)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human calcyphosine protein (His tag N-Terminus) (AB105131)

15% SDS-PAGE showing ab105131 (3 μg) at approximately 23.1 kDa.

关键信息

纯度

>95% SDS-PAGE

ab105131 is purified using conventional chromatography techniques.

表达系统

Escherichia coli

标签

His tag N-Terminus

应用

SDS-PAGE, Mass Spec

applications

生物活性

No

访问

Q13938

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.316% Tris HCl, 0.0308% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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搭配使用产品

Primary Antibodies

AB250894

Anti-calcyphosine antibody [EPR15631] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-calcyphosine antibody [EPR15631] - BSA and Azide free (AB250894)

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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序列信息

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFDSSEKDGQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL","proteinLength":"Full Length","predictedMolecularWeight":"23.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":189,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q13938","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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性能和储存信息

形式
Liquid
运输条件
Blue Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Calcyphosine also known as CAPS is a calcium-binding protein with a molecular mass of approximately 22 kDa. It plays a role in intracellular calcium signaling. Calcyphosine expression occurs widely in multiple tissues with high levels observed in the thyroid gland and epithelial tissues. It binds calcium ions impacting cellular processes such as signal transduction and cell communication.
Biological function summary

Calcyphosine influences several cellular functions related to calcium homeostasis and signaling. It does not form part of any larger complex but modulates cellular activities by regulating calcium ion concentrations inside cells. This regulation is critical for functions like muscle contraction hormone secretion and neurotransmitter release. Its presence in different tissues suggests diverse roles depending on the cellular environment.

Pathways

Calcyphosine plays a role in calcium-dependent pathways significant for maintaining cellular activities. It intersects with the calcium signaling pathway affecting proteins like calmodulin and calcineurin which further mediate various cellular responses. These interactions alter signal transmission processes vital for cell responses and adaptations.

Studies have noted calcyphosine's involvement in thyroid-related conditions and some cancers. Altered expression levels link the protein to thyroid disorders potentially affecting thyroid hormone production and regulation. Calcyphosine's interaction with proteins like TSH receptor and thyroid transcription factors highlights its role in thyroid function and its potential influence on thyroid pathology and neoplastic conditions.
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常规信息

功能

Calcium-binding protein. May play a role in cellular signaling events (Potential).

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产品实验方案

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靶点信息

Calcium-binding protein. May play a role in cellular signaling events (Potential).
See full target information Calcyphosin
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of neuroscience : the official journal 40:8976-8993 PubMed33055278

2020

Piezo2 Mediates Low-Threshold Mechanically Evoked Pain in the Cornea.

Applications

Unspecified application

Species

Unspecified reactive species

Jorge Fernández-Trillo,Danny Florez-Paz,Almudena Íñigo-Portugués,Omar González-González,Ana Gómez Del Campo,Alejandro González,Félix Viana,Carlos Belmonte,Ana Gomis
View all publications
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