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AB196105

重组人BRD9蛋白(Active)

Recombinant human BRD9 protein (Active)

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Recombinant human BRD9 protein (Active) is a Human Fragment protein, in the 135 to 242 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, FuncS.

查看别名

UNQ3040/PRO9856, BRD9, Bromodomain-containing protein 9, Rhabdomyosarcoma antigen MU-RMS-40.8

2 Images
Functional Studies - Recombinant human BRD9 protein (Active) (AB196105)
  • FuncS

Supplier Data

Functional Studies - Recombinant human BRD9 protein (Active) (AB196105)

Example of specific activity of ab196105

SDS-PAGE - Recombinant human BRD9 protein (Active) (AB196105)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant human BRD9 protein (Active) (AB196105)

4-20% SDS Page analysis of ab196105 (2 μg)

关键信息

纯度

>95% SDS-PAGE

表达系统

Escherichia coli

标签

GST tag N-Terminus

应用

FuncS, SDS-PAGE

applications

生物活性

Yes

生物学活性

Assay was performed using BRD9 Inhibitor Screening Assay Kit.

访问

Q9H8M2

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.64% Sodium chloride, 0.63% Tris HCl, 0.02% Potassium chloride

storage-buffer

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.</p>" } } }

序列信息

[{"sequence":"ENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAA","proteinLength":"Fragment","predictedMolecularWeight":"39 kDa","actualMolecularWeight":null,"aminoAcidEnd":242,"aminoAcidStart":135,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9H8M2","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

性能和储存信息

运输条件
Dry Ice
推荐的短期储存条件
-80°C
推荐的长期储存条件
-80°C
储存信息
Avoid freeze / thaw cycle
True

特殊说明

形式

Liquid

常规信息

功能

Plays a role in chromatin remodeling and regulation of transcription (PubMed : 22464331, PubMed : 26365797). Acts as a chromatin reader that recognizes and binds acylated histones : binds histones that are acetylated and/or butyrylated (PubMed : 26365797). Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed : 29374058). Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR) (PubMed : 32457312).

产品实验方案

靶点信息

Plays a role in chromatin remodeling and regulation of transcription (PubMed : 22464331, PubMed : 26365797). Acts as a chromatin reader that recognizes and binds acylated histones : binds histones that are acetylated and/or butyrylated (PubMed : 26365797). Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed : 29374058). Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR) (PubMed : 32457312).
See full target information BRD9

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