AB109849

重组人BOB1蛋白

Name: 重组人BOB1蛋白 (ab109849)| Abcam中文官网
Brand: Abcam Limited
SKU: AB109849
Price: 4870 CNY
Availability: InStock

Recombinant Human BOB1 protein

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(1 Publication)

Recombinant Human BOB1 protein is a Human Full Length protein, in the 1 to 256 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

查看别名

BOB1, OBF1, POU2AF1, POU domain class 2-associating factor 1, B-cell-specific coactivator OBF-1, BOB-1, OCA-B, OCT-binding factor 1

2 Images

SDS-PAGE - Recombinant Human BOB1 protein (AB109849)

SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human BOB1 protein (AB109849)

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human BOB1 protein (AB109849)

15% SDS-PAGE (3 μg)

关键信息

纯度

>85% SDS-PAGE

表达系统

Escherichia coli

应用

SDS-PAGE

applications

生物活性

访问

Q16633

不含动物源

不含载体蛋白

种属

Human

存储溶液

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.316% Tris HCl

storage-buffer

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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序列信息

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRRKRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTRSSATPAVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF","proteinLength":"Full Length","predictedMolecularWeight":"29.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":256,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q16633","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

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性能和储存信息

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

False

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特殊说明

形式

Liquid

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常规信息

功能

Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2 (PubMed : 7859290). It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2 (PubMed : 7779176). It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2 (PubMed : 7779176). It is essential for the response of B-cells to antigens and required for the formation of germinal centers (PubMed : 7623806, PubMed : 7859290). Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator (By similarity).

序列相似性

Belongs to the POU2AF family.

翻译后修饰

Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.

亚细胞定位

Nucleus

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产品实验方案

Visit the General protocols
Visit the Troubleshooting

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靶点信息

See full target information POU2AF1

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of neuroinflammation 16:141 PubMed31288834

2019

The effects of human immunoglobulin G on enhancing tissue protection and neurobehavioral recovery after traumatic cervical spinal cord injury are mediated through the neurovascular unit.

Applications

Unspecified application

Species

Unspecified reactive species

Jonathon Chon Teng Chio,Jian Wang,Anna Badner,James Hong,Vithushan Surendran,Michael G Fehlings

View all publications

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重组人BOB1蛋白

Recombinant Human BOB1 protein

SDS-PAGE - Recombinant Human BOB1 protein (AB109849)

SDS-PAGE - Recombinant Human BOB1 protein (AB109849)

关键信息

纯度

表达系统

标签

应用

生物活性

访问

不含动物源

不含载体蛋白

种属

存储溶液