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AB94350

重组人BMP9蛋白(Active)

Recombinant human BMP9 protein (Active)

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Recombinant human BMP9 protein (Active) is a Human Full Length protein, in the 320 to 429 aa range, expressed in CHO cells, with >95%, suitable for SDS-PAGE, HPLC, FuncS.

查看别名

BMP9, GDF2, Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9

关键信息

纯度

>95% SDS-PAGE

表达系统

CHO cells

标签

Tag free

应用

HPLC, FuncS, SDS-PAGE

applications

生物活性

Yes

生物学活性

Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.9 ng/ml.

访问

Q9UK05

不含动物源

No

不含载体蛋白

No

种属

Human

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

序列信息

[{"sequence":"SAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR","proteinLength":"Full Length","predictedMolecularWeight":"24.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":429,"aminoAcidStart":320,"nature":"Recombinant","expressionSystem":"CHO cells","accessionNumber":"Q9UK05","tags":[]}]

性能和储存信息

运输条件
Blue Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
True

特殊说明

形式

Lyophilized

附加说明

Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).

常规信息

功能

Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

序列相似性

Belongs to the TGF-beta family.

翻译后修饰

A reversible disulfide bond can be formed between the two subunits in the homodimer; this has no effect on GDF2 activity.

产品实验方案

靶点信息

Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
See full target information GDF2

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