重组人Bim蛋白(denatured) (ab130020)
Key features and details
- Expression system: Escherichia coli
- Purity: > 80% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
描述
-
产品名称
重组人Bim蛋白(denatured)
参阅全部 Bim 蛋白酶 -
纯度
> 80 % SDS-PAGE. -
表达系统
Escherichia coli -
Accession
-
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
序列
MGSSHHHHHH SSGLVPRGSH MGSHMAKQPS DVSSECDREG RQLQPAERPP QLRPGAPTSL QTEPQDRSPA PMSCDKSTQT PSPPCQAFNH YLSAMASMRQ AEPADMRPEI WIAQELRRIG DEFNAYYARR VFLNNYQAAE DHPRMVILRL LRYIVRLVWR MH -
预测分子量
19 kDa including tags -
氨基酸
1 to 138 -
标签
His tag N-Terminus
-
-
描述
重组人Bim蛋白
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab130020 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
-
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 12.01% Urea, 0.08% DTT, 0.32% Tris HCl, 20% Glycerol (glycerin, glycerine), 1.75% Sodium chloride
常规信息
-
别名
- BCL2 like 11
- B2L11_HUMAN
- BAM
see all -
功能
Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis. -
组织特异性
Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are ubiquitously expressed with a tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney. -
序列相似性
Belongs to the Bcl-2 family. -
结构域
The BH3 motif is required for Bcl-2 binding and cytotoxicity. -
细胞定位
Mitochondrion and Endomembrane system. Associated with intracytoplasmic membranes. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab130020 尚未被引用在任何文献中。