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重组人ATP6V1A蛋白(ab132441)

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SDS-PAGE - Recombinant Human ATP6V1A protein (ab132441)

    Key features and details

    • Expression system: Wheat germ
    • Suitable for: ELISA, WB, SDS-PAGE

    描述

    • 产品名称

      重组人ATP6V1A蛋白

    • 表达系统

      Wheat germ

    • Accession

      P38606

    • 蛋白长度

      Full length protein

    • 无动物成分

      No

    • 性质

      Recombinant

      • 种属

        Human

      • 序列

        MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSEL VGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFD GIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWDFTPCKNLRVGSHITGG DIYGIVSENSLIKHKIMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGVK EKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPG AFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDG KVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADS TSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPER EGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNW LISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKAS LAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMIAFYDM ARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSD YAQLLEDMQNAFRSLED

      • 预测分子量

        94 kDa including tags

      • 氨基酸

        1 to 617

    技术指标

    Our Abpromise guarantee covers the use of ab132441 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      ELISA

      Western blot

      SDS-PAGE

    • 形式

      Liquid
    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    常规信息

    • 别名

      • 70kDa subunit
      • ATP6A1
      • ATP6V1A
      • ATP6V1A1
      • ATPase H+ transporting lysosomal subunit A1
      • ATPase H+ transporting, lysosomal 70kDa V1 subunit A
      • H(+) transporting two sector ATPase subunit A
      • H+ transporting ATPase chain A vacuolar (VA68 type)
      • HO68
      • OTTHUMP00000214746
      • V ATPase 69 kDa subunit 1
      • V ATPase A subunit 1
      • V ATPase subunit A 1
      • V-ATPase 69 kDa subunit
      • V-ATPase subunit A
      • V-type proton ATPase catalytic subunit A
      • VA68
      • Vacuolar ATP synthase catalytic subunit A ubiquitous isoform
      • Vacuolar ATPase isoform VA68
      • Vacuolar proton pump alpha subunit 1
      • Vacuolar proton pump subunit alpha
      • VATA_HUMAN
      • Vma1
      • VPP2
      see all

    • 功能

      Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

    • 组织特异性

      Present in all tissues analyzed.

    • 序列相似性

      Belongs to the ATPase alpha/beta chains family.
    • Information by UniProt

    图片

    • SDS-PAGE - Recombinant Human ATP6V1A protein (ab132441)
      SDS-PAGE - Recombinant Human ATP6V1A protein (ab132441)
      12.5% SDS-PAGE analysis of ab132441 stained with Coomassie Blue.

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (1)

    发表研究结果有使用 ab132441？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab132441 被引用在 1 文献中.

    • Chung CY  et al. Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition. Nat Chem Biol 15:776-785 (2019). PubMed: 31285595

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