重组人ARMET/ARP蛋白(ab123227)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE, HPLC
描述
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产品名称
重组人ARMET/ARP蛋白
参阅全部 ARMET/ARP 蛋白酶 -
生物活性
Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 15-25 µg/ml.
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纯度
> 98 % SDS-PAGE.
Purity is greater than 98% by SDS-PAGE gel and HPLC analyses. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL -
预测分子量
18 kDa -
氨基酸
25 to 182
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab123227 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
HPLC
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形式
Lyophilized -
补充说明
This product was previously labelled as ARMET
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -80°C.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶For lot specific reconstitution information please contact our Scientific Support Team.
常规信息
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别名
- Arginine rich mutated in early stage tumors
- Arginine rich protein
- Arginine-rich protein
see all -
功能
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. -
序列相似性
Belongs to the ARMET family. -
结构域
The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response. -
翻译后修饰
May contain sialic acid residues. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (1)
ab123227 被引用在 1 文献中.
- Sun T et al. Cold Plasma Irradiation Attenuates Atopic Dermatitis via Enhancing HIF-1α-Induced MANF Transcription Expression. Front Immunol 13:941219 (2022). PubMed: 35911675
