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AB109953

重组人 ARL11 蛋白 (His tag N-Terminus)

Recombinant Human ARL11 protein (His tag N-Terminus)

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Recombinant Human ARL11 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 196 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

查看别名

ARLTS1, ARL11, ADP-ribosylation factor-like protein 11, ADP-ribosylation factor-like tumor suppressor protein 1

1 Images
SDS-PAGE - Recombinant Human ARL11 protein (AB109953)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human ARL11 protein (AB109953)

15% SDS-PAGE analysis of ab109953 (3μg)

关键信息

纯度

>90% SDS-PAGE

表达系统

Escherichia coli

标签

His tag N-Terminus

应用

SDS-PAGE, Mass Spec

applications

生物活性

No

访问

Q969Q4

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 30% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.08% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.03% EDTA

storage-buffer

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

序列信息

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPGHVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGVPFLVLANKQEAPDALPLLKIRNRLSLERFQDHCWELRGCSALTGEGLPEALQSLWSLLKSRSCMCLQARAHGAERGDSKRS","proteinLength":"Full Length","predictedMolecularWeight":"23.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":196,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q969Q4","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

性能和储存信息

运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

ARL11 also known as ADP-ribosylation factor-like 11 is a small GTPase protein involved in cellular processes such as vesicle trafficking and signal transduction. This protein has a mass of approximately 20 kilodaltons. ARL11 is expressed in various tissues with notable levels in the pancreas spleen and peripheral blood leukocytes. Researchers frequently study this target due to its role in cellular mechanics and its diverse tissue expression pattern.
Biological function summary

ARL11 regulates cell growth and apoptosis influencing the cellular response to stress. This protein often functions as part of molecular complexes interacting with elements of the cellular machinery to modulate the cell cycle and cellular proliferation. Through these interactions ARL11 can impact the integrity and functionality of cellular processes which positions it as a point of interest in understanding cell regulation and stress responses.

Pathways

ARL11 plays roles in both the apoptosis and signal transduction pathways. It interacts with proteins such as p53 and other members of the Ras superfamily which are involved in controlling cell cycle progression and apoptosis. These pathways highlight ARL11's involvement in maintaining proper cellular function and response to external and internal signals linking it to broader cellular activity networks.

Researchers associate ARL11 with certain types of cancers including pancreatic cancer and lymphomas. Its interaction with proteins like p53 suggests a role in tumor suppression and regulation of cell cycle checkpoints. Changes in ARL11 function or expression may contribute to oncogenic processes suggesting its potential as a target for therapeutic interventions in cancer treatments.

特殊说明

形式

Liquid

附加说明

ab109953 was purified using conventional chromatography techniques

常规信息

功能

May play a role in apoptosis. May act as a tumor suppressor.

序列相似性

Belongs to the small GTPase superfamily. Arf family.

产品实验方案

靶点信息

May play a role in apoptosis. May act as a tumor suppressor.
See full target information ARL11

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