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AB132786

重组人 APMAP 蛋白 (GST tag N-Terminus)

Recombinant Human APMAP protein (GST tag N-Terminus)

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Recombinant Human APMAP protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 416 aa range, expressed in Wheat germ, suitable for SDS-PAGE, ELISA, WB.

查看别名

C20orf3, UNQ1869/PRO4305, APMAP, Adipocyte plasma membrane-associated protein, Protein BSCv

1 Images
SDS-PAGE - Recombinant Human APMAP protein (GST tag N-Terminus) (AB132786)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human APMAP protein (GST tag N-Terminus) (AB132786)

12.5% SDS-PAGE analysis of ab132786 stained with Coomassie Blue.

关键信息

表达系统

Wheat germ

标签

GST tag N-Terminus

应用

WB, SDS-PAGE, ELISA

applications

生物活性

No

访问

Q9HDC9

不含动物源

No

不含载体蛋白

No

种属

Human

存储溶液

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

序列信息

[{"linker":null,"sequence":"MSEADGLRQRRPLRPQVVTDDDGQAPEAKDGSSFSGRVFRVTFLMLAVSLTVPLLGAMMLLESPIDPQPLSFKEPPLLLGVLHPNTKLRQAERLFENQLVGPESIAHIGDVMFTGTADGRVVKLENGEIETIARFGSGPCKTRDDEPVCGRPLGIRAGPNGTLFVADAYKGLFEVNPWKREVKLLLSSETPIEGKNMSFVNDLTVTQDGRKIYFTDSSSKWQRRDYLLLVMEGTDDGRLLEYDTVTREVKVLLDQLRFPNGVQLSPAEDFVLVAETTMARIRRVYVSGLMKGGADLFVENMPGFPDNIRPSSSGGYWVGMSTIRPNPGFSMLDFLSERPWIKRMIFKLFSQETVMKFVPRYSLVLELSDSGAFRRSLHDPDGLVATYISEVHEHDGHLYLGSFRSPFLCRLSLQAV","proteinLength":"Full Length","predictedMolecularWeight":"72.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":416,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9HDC9","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

性能和储存信息

形式
Liquid
纯化工艺
Proprietary technique
运输条件
Dry Ice
推荐的短期储存条件
-80°C
推荐的长期储存条件
-80°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

APMAP also known as adipocyte plasma membrane-associated protein is an integral membrane protein that weighs approximately 45 kDa. APMAP localizes primarily in adipose tissues and hepatocytes. This protein resides within both the plasma membrane and intracellular compartments. APMAP participates in lipid metabolism through its interactions with various protein complexes. Its expression levels vary across different tissues reflecting a specialized role in certain physiological functions.
Biological function summary

APMAP functions within the modulation of lipid homeostasis especially in adipocytes. It shows involvement in triglyceride metabolism by regulating enzyme activity responsible for lipid turnover. APMAP acts as a part of a protein complex that includes enzymes affecting lipid storage and release. Through such interactions APMAP influences key biological processes that maintain lipid balance supporting energy homeostasis in mammals.

Pathways

APMAP integrates into the lipid metabolic pathway particularly those impacting triglyceride storage and hydrolysis. APMAP associates with proteins like perilipin which also participate in lipid droplet formation and breakdown. Additionally APMAP's involvement with AMP-activated protein kinase (AMPK) signaling influences cellular energy status linking it to pathways controlling metabolism and energy sensing.

APMAP shows association with metabolic syndrome and type 2 diabetes. Its role in lipid metabolism connects APMAP to insulin signaling pathways where altered expression or function may contribute to these metabolic disorders. APMAP's relationship with adiponectin a protein with anti-diabetic properties indicates its potential impact on glucose metabolism dysregulation. Understanding APMAP's function helps unravel molecular underpinnings of metabolic diseases offering insights for targeted therapeutic approaches.

常规信息

功能

Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.

序列相似性

Belongs to the strictosidine synthase family.

产品实验方案

靶点信息

Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.
See full target information APMAP

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