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重组人Anterior Gradient 2蛋白(ab64013)

Submit a review Q&A (2)References (2)
SDS-PAGE - Recombinant Human Anterior Gradient 2 protein (ab64013)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE

    描述

    • 产品名称

      重组人Anterior Gradient 2蛋白

    • 纯度

      > 90 % SDS-PAGE.

    • 表达系统

      Escherichia coli

    • Accession

      O95994

    • 蛋白长度

      Full length protein

    • 无动物成分

      No

    • 性质

      Recombinant

      • 种属

        Human

      • 序列

        MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSM RDT TVKPGAKKDT KDSRPKLPQT LSRGWGDQLI WTQTYEEALY KSKTSNKPLM IIHHLDECPH SQALKKVFAE NKEIQKLAEQ FVLLNLVYET TDKHLSPDGQ YVPRIMFVDP SLTVRADITG RYSNRLYAYE PADTALLLDN MKKALKLLKT EL

      • 预测分子量

        22 kDa

      • 氨基酸

        21 to 175

      • 标签

        His tag N-Terminus

    技术指标

    Our Abpromise guarantee covers the use of ab64013 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      SDS-PAGE

    • 形式

      Liquid
    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 10% Glycerol (glycerin, glycerine), 0.03% EDTA, 0.32% Tris HCl

    常规信息

    • 别名

      • AG 2
      • AG 2 protein
      • AG-2
      • AG2
      • AG2 protein
      • AGR 2
      • AGR2
      • AGR2_HUMAN
      • anterior gradient 2 homolog
      • Anterior gradient 2 homolog (Xenopus laevis)
      • Anterior gradient 2, protein disulphide isomerase family member
      • Anterior gradient 2, Xenopus, homolog of
      • Anterior gradient homolog 2
      • Anterior gradient protein 2 homolog
      • Epididymis secretory protein Li 116
      • GOB 4
      • GOB4
      • HAG 2
      • hAG-2
      • hAG2
      • HAG2/R
      • HEL S 116
      • HPC 8
      • hPC8
      • PDIA17
      • Protein disulfide isomerase family A member 17
      • secreted cement gland homolog
      • Secreted cement gland protein XAG 2 homolog
      • Secreted cement gland protein XAG-2 homolog
      • Secreted cement gland protein XAG2 homolog
      • XAG 2
      • XAG2
      see all

    • 功能

      Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.

    • 组织特异性

      Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.

    • 序列相似性

      Belongs to the AGR family.

    • 细胞定位

      Secreted. Endoplasmic reticulum.
    • Information by UniProt

    图片

    • SDS-PAGE - Recombinant Human Anterior Gradient 2 protein (ab64013)
      SDS-PAGE - Recombinant Human Anterior Gradient 2 protein (ab64013)

      SDS-PAGE analysis of ab64013 (3µg) under reducing condition and visualized by coomassie blue stain.

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (2)

    发表研究结果有使用 ab64013？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab64013 被引用在 2 文献中.

    • Stojak M  et al. Protein Disulphide Isomerase A1 Is Involved in the Regulation of Breast Cancer Cell Adhesion and Transmigration via Lung Microvascular Endothelial Cells. Cancers (Basel) 12:N/A (2020). PubMed: 33023153
    • Arumugam T  et al. New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice. Mol Cancer Ther 14:941-51 (2015). PubMed: 25646014

    客户评价及客户问答

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    1-2 of 2 Abreviews or Q&A

    Question

    What is the sequence of this peptide. You have advertised it as full-length.

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    Answer

    Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products. I am sorry this peptide wasshorter than stated on the datasheet and for the inconvenience this has caused. As requested, I have issued a free of charge replacement with the order number xxxx. To check the status of the order please contact our Customer Service team and reference this number. Please note that this free of charge replacement vial is also covered by our Abpromise guarantee. Should you still be experiencing difficulties, or if you have any further questions, please do not hesitate to let us know. I wish you the best of luck with your research.

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    Question

    Endotoxin free?

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    Answer

    The endotoxin level is above 1.0 EU per 1 ug of protein by LAL method. Exact endotoxin level is unknown.

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