重组人Angiopoietin 2/ANG2蛋白(ab123226)
Key features and details
- Expression system: CHO cells
- Purity: > 95% SDS-PAGE
- Active: Yes
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE, HPLC, Functional Studies
描述
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产品名称
重组人Angiopoietin 2/ANG2蛋白
参阅全部 Angiopoietin 2/ANG2 蛋白酶 -
纯度
> 95 % SDS-PAGE.
Purity is greater than 95% by SDS-PAGE gel and HPLC analyses. -
表达系统
CHO cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
DAPLEYDDSV QRLQVLENIM ENNTQWLMKL ENYIQDNMKK EMVEIQQNAV QNQTAVMIEI GTNLLNQTAE QTRKLTDVEA QVLNQTTRLE LQLLEHSLST NKLEKQILDQ TSEINKLQDK NSFLEKKVLA MEDKHIIQLQ SIKEEKDQLQ VLVSKQNSII EELEKKIVTA TVNNSVLQKQ QHDLMETVNN LLTMMSTSNS AKDPTVAKEE QISFRDCAEV FKSGHTTNGI YT -
氨基酸
68 to 299 -
标签
His tag C-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab123226 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
HPLC
Functional Studies
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形式
Lyophilized -
补充说明
Determined by its ability to stimulate tubulogenesis in HUVEC cells using a concentration of 0.2µg/ml.This product was previously labelled as Angiopoietin 2
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -20°C.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶We recommend storing the lyophilised product at -20ºC. If the product has been reconstituted, then we recommend storing with a carrier protein, such as 0.1% BSA in working aliquots at -20ºC to -80ºC for 3 months.
常规信息
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别名
- AGPT 2
- Agpt2
- ANG 2
see all -
功能
Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. -
序列相似性
Contains 1 fibrinogen C-terminal domain. -
结构域
The Fibrinogen C-terminal domain mediates interaction with the TEK/TIE2 receptor. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab123226 尚未被引用在任何文献中。