重组人AFM蛋白(His tag)
Recombinant Human AFM protein (His tag)
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Recombinant Human AFM protein (His tag) is a Human Full Length protein, in the 1 to 599 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
查看别名
ALB2, ALBA, AFM, Afamin, Alpha-albumin, Alpha-Alb
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human AFM protein (His tag) (AB276516)
SDS-PAGE analysis of ab276516
反应性数据
序列信息
性能和储存信息
形式
运输条件
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
AFM plays a central role in the transport of lipids and vitamins particularly vitamin E throughout the body. It acts independently and does not participate in large protein complexes. AFM shows interactions with other lipid-binding proteins modulating their activities and ensuring efficient distribution of essential nutrients. Such interactions highlight the importance of AFM in maintaining cellular homeostasis and protecting cells from oxidative damage.
Pathways
AFM actively participates in metabolic and vitamin transport pathways collaborating with proteins like albumin and transthyretin. It notably influences lipid metabolism and antioxidative pathways thereby contributing to overall cellular defense mechanisms. AFM's functionality intertwines with the activities of these proteins indicating its essential role in finely tuned biological processes especially those involving lipid and vitamin management.
常规信息
功能
Functions as a carrier for hydrophobic molecules in body fluids (Probable). Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B (PubMed : 26902720). Binds vitamin E (PubMed : 12463752, PubMed : 15952736). May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient (PubMed : 15952736). May be involved in the transport of vitamin E across the blood-brain barrier (PubMed : 19046407).
序列相似性
Belongs to the ALB/AFP/VDB family.
翻译后修饰
N-glycosylated; more than 90% of the glycans are sialylated.
靶点信息
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