重组HIV1 tat蛋白(ab83353)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Suitable for: Blocking, WB, SDS-PAGE
描述
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产品名称
重组HIV1 tat蛋白 -
生物活性
ab83353 reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum. -
纯度
> 90 % SDS-PAGE. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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氨基酸
1 to 101
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相关产品
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Matched antibody pairs
技术指标
Our Abpromise guarantee covers the use of ab83353 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Blocking
Western blot
SDS-PAGE
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形式
Lyophilized -
补充说明
ab83353 reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -80°C.
Constituent: 0.1% Glycerol
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复溶The protein should be reconstituted in apirogenic sterile water or PBS buffer. The reconstituted solution has to be used immediately.
常规信息
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别名
- p14
- Protein Tat
- Transactivating regulatory protein
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相关性
HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR. -
细胞定位
Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (4)
ab83353 被引用在 4 文献中.
- Alomar FA et al. HIV-Tat Exacerbates the Actions of Atazanavir, Efavirenz, and Ritonavir on Cardiac Ryanodine Receptor (RyR2). Int J Mol Sci 24:N/A (2022). PubMed: 36613717
- Cheng D et al. The nuclear transcription factor, TAF7, is a cytoplasmic regulator of protein synthesis. Sci Adv 7:eabi5751 (2021). PubMed: 34890234
- Zhou F et al. HIV-1 Tat enhances purinergic P2Y4 receptor signaling to mediate inflammatory cytokine production and neuronal damage via PI3K/Akt and ERK MAPK pathways. J Neuroinflammation 16:71 (2019). PubMed: 30947729
- Qu J et al. The Tat protein of human immunodeficiency virus-1 enhances hepatitis C virus replication through interferon gamma-inducible protein-10. BMC Immunol 13:15 (2012). PubMed: 22471703
