重组HIV1 Nef蛋白(Beta-Galactosidase) (ab49060)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: ELISA, WB
描述
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产品名称
重组HIV1 Nef蛋白(Beta-Galactosidase)
参阅全部 HIV1 Nef 蛋白酶 -
生物活性
Reacts strongly with human HIV positive serum. -
纯度
> 95 % SDS-PAGE. -
表达系统
Escherichia coli -
蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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额外的序列信息
Fused with β-galactosidase at the N-terminus.
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技术指标
Our Abpromise guarantee covers the use of ab49060 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
ELISA
Western blot
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形式
Liquid -
补充说明
Reacts strongly with human HIV positive serum. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: 0.106% Sodium carbonate, 0.1092% Beta mercaptoethanol, 0.292% EDTA
常规信息
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别名
- C terminal core protein
- F protein
- Nef
see all -
相关性
Nef is a early protein that appears to play a role in optimizing the host cell environment for viral replication without causing cell death by apoptosis. Nef enhances virus infectivity and pathogenicity. It down modulates surface MHC I molecules and internalized molecules are sequested to the trans-Golgi network. The number of cell surface CD4 antigen are decreased by interacting with the Src family kinase LCK thereby inducing LCK CD4 dissociation and by increasing clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab49060 尚未被引用在任何文献中。