重组HIV1 Nef蛋白(ab63996)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Suitable for: SDS-PAGE
描述
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产品名称
重组HIV1 Nef蛋白
参阅全部 HIV1 Nef 蛋白酶 -
纯度
> 90 % SDS-PAGE.
Highly purified by several steps of chromatography. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
HIV-1 -
序列
MGGKWSKSSVVGWPTVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAA TNAACAWLEA QEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLE GLIHSQRRQDILDLWIYHTQGY FPDWQNYTPGPGVRYPLTFGWCYKLV PVEPDKVEEANKGENTSLLHPVSLHGMDDPEREV LEWRFDSRLAFHHV ARELHPEYFKNC -
氨基酸
1 to 206
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相关产品
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Corresponding Antibody
技术指标
Our Abpromise guarantee covers the use of ab63996 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
补充说明
ab63996 has been derived from infectious plasmid clone pNL4-3 and belongs to Group B of HIV-1. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 6
Constituents: 0.078% Beta mercaptoethanol, 0.316% Tris HCl, 50% Glycerol (glycerin, glycerine), 0.29% Sodium chloride
常规信息
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别名
- C terminal core protein
- F protein
- Nef
see all -
相关性
Nef is a early protein that appears to play a role in optimizing the host cell environment for viral replication without causing cell death by apoptosis. Nef enhances virus infectivity and pathogenicity. It down modulates surface MHC I molecules and internalized molecules are sequested to the trans-Golgi network. The number of cell surface CD4 antigen are decreased by interacting with the Src family kinase LCK thereby inducing LCK CD4 dissociation and by increasing clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation.
图片
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SDS-PAGE - Recombinant HIV1 Nef protein (ab63996)Polyacrylamide gel electrophoresis of ab63996.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab63996 尚未被引用在任何文献中。