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AB106864

重组 E. coli deoC 蛋白 (His tag N-Terminus)

Recombinant E. coli deoC protein (His tag N-Terminus)

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Recombinant E. coli deoC protein (His tag N-Terminus) is a Escherichia coli K-12 Full Length protein, in the 1 to 259 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.

查看别名

dra, thyR, b4381, JW4344, deoC, Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase

2 Images
SDS-PAGE - Recombinant E. coli deoC protein (His tag N-Terminus) (AB106864)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant E. coli deoC protein (His tag N-Terminus) (AB106864)

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

SDS-PAGE - Recombinant E. coli deoC protein (His tag N-Terminus) (AB106864)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant E. coli deoC protein (His tag N-Terminus) (AB106864)

15% SDS-PAGE analysis of 3μg ab106864.

关键信息

纯度

>95% SDS-PAGE

ab106864 is purified using conventional chromatography techniques.

表达系统

Escherichia coli

标签

His tag N-Terminus

应用

SDS-PAGE, Mass Spec

applications

生物活性

No

访问

P0A6L0

不含动物源

No

不含载体蛋白

No

种属

Escherichia coli K-12

存储溶液

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.316% Tris HCl, 0.0308% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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搭配使用产品

Proteins & Peptides

AB104677

Recombinant E. coli fimC protein (His tag N-Terminus)

SDS-PAGE - Recombinant E. coli fimC protein (His tag N-Terminus) (AB104677)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Proteins & Peptides

AB107143

Recombinant E. coli glsA1 protein (His tag N-Terminus)

SDS-PAGE - Recombinant E. coli glsA1 protein (His tag N-Terminus) (AB107143)

  • 0
  • 0
Secondary Antibodies

AB41500

Rabbit Anti-Chicken IgY H&L (15nm Gold)

  • 0
  • 0
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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序列信息

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIDIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY","proteinLength":"Full Length","predictedMolecularWeight":"29.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":259,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P0A6L0","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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性能和储存信息

形式
Liquid
运输条件
Blue Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

DeoC also known as deoxyribose-phosphate aldolase is an enzyme that plays a mechanical role in catalyzing the cleavage of deoxyribose-5-phosphate into glyceraldehyde-3-phosphate and acetaldehyde. This enzyme weighs approximately 23 kDa. deoC is typically expressed in bacterial cells especially within Escherichia coli where it is involved in DNA metabolism by-products breakdown.
Biological function summary

The enzyme deoC functions as part of the pentose phosphate pathway critical for cellular functions by contributing to nucleotide synthesis and energy generation. In its role deoC doesn't form part of a larger complex but functions independently. It acts on intermediates in nucleotide salvage pathways therefore playing a role in optimizing cellular resources.

Pathways

DeoC integrates into the non-oxidative branch of the pentose phosphate pathway facilitating the conversion of sugar phosphates. It interacts with other enzymes like ribose-5-phosphate isomerase and transketolase which are pivotal in these metabolic pathways. These interactions highlight its essential role in connecting nucleotide metabolism and glycolysis.

Researchers have explored deoC's implications in bacterial infections. Its activity significantly impacts the pathogen's survival and virulence influencing disorders related to bacterial persistence. While deoC itself is not directly linked to human diseases it plays an important role in bacterial life cycle and disrupts the metabolic processes that can reduce the bacterial load. This makes it an indirect target for antibiotic strategies.
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常规信息

功能

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate (PubMed : 11598300, PubMed : 17905878, PubMed : 6749498). Can also catalyze the double aldol condensation of three acetaldehyde molecules, leading to the formation of 2,4,6-trideoxyhexose (Ref.5).

序列相似性

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.

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产品实验方案

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靶点信息

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate (PubMed : 11598300, PubMed : 17905878, PubMed : 6749498). Can also catalyze the double aldol condensation of three acetaldehyde molecules, leading to the formation of 2,4,6-trideoxyhexose (Ref.5).
See full target information deoC
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