重组Cytomegalovirus Glycoprotein B (ab43040)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: ELISA, WB
描述
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产品名称
重组Cytomegalovirus Glycoprotein B
参阅全部 Cytomegalovirus Glycoprotein B 蛋白酶 -
生物活性
Immunoreactive with sera of CMV infected individuals. -
纯度
> 95 % SDS-PAGE.
Sepharose derived purification. -
表达系统
Escherichia coli -
蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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额外的序列信息
The protein contains the Cytomegalovirus (CMV) gB immunodominant regions.
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描述
重组Cytomegalovirus Glycoprotein B
技术指标
Our Abpromise guarantee covers the use of ab43040 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
ELISA
Western blot
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 7.20
Constituents: 0.395% Tris HCl, 0.0292% EDTA, 50% Glycerol
常规信息
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别名
- CMV glycoprotein B
- Glycoprotein B
- HCMV
see all -
相关性
Human cytomegalovirus (HCMV) glycoprotein B (gB) is an abundant virion envelope protein that has been shown to be essential for the infectivity of HCMV. HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of virus neutralizing antibodies are directed at gB. -
细胞定位
Virus envelope.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab43040 被引用在 5 文献中.
- Gomes AC et al. The cytomegalovirus gB/MF59 vaccine candidate induces antibodies against an antigenic domain controlling cell-to-cell spread. Nat Commun 14:1041 (2023). PubMed: 36823200
- Davies EL et al. HCMV carriage in the elderly diminishes anti-viral functionality of the adaptive immune response resulting in virus replication at peripheral sites. Front Immunol 13:1083230 (2022). PubMed: 36591233
- Richardson SI et al. IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody. PLoS Pathog 15:e1008064 (2019). PubMed: 31841557
- Pires F et al. A rapid magnetic particle-based enzyme immunoassay for human cytomegalovirus glycoprotein B quantification. J Pharm Biomed Anal 156:372-378 (2018). PubMed: 29758495
- Crawford LB et al. Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice. Sci Rep 7:937 (2017). ELISA . PubMed: 28428537